Results 61 to 70 of about 4,942,884 (242)

UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen   +13 more
wiley   +1 more source

An assessment of the impact of environmental factors on the quality of post-mortem DNA profiling. [PDF]

open access: yes, 2009
DNA profiling has ignited public interest and consequently their expectations for the capabilities of forensic criminal and science investigations. The prospect of characterising the genetic makeup of individuals or trace samples from a wide variety of ...
Gunawardane, Dalugama Mudiyanselage Don Dimuth Nilanga
core  

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao   +3 more
wiley   +1 more source

La desfacialización: una practica mutilatoria post mortem

open access: yesRevista Argentina de Antropología Biológica, 2010
RESUMEN Se da a conocer una práctica mutilatoria post mortem que hasta el presente nunca fuera reportada en cráneos de aborígenes del territorio nacional consistente en la ablación completa de la cara. Se describen tres ejemplares que la presentan, todos
Alberto J. Marcellino   +2 more
doaj   +2 more sources

Exclusiones post mortem. Esclavitud, suicidio y derecho de sepultura

open access: yesDirāsāt Hispānicas, 2015
La negación del derecho de sepultura a esclavos y colonos asiáticos no bautizados fue una práctica de exclusión que se extendió casi hasta el final de la esclavitud.
Pedro Marqués de Armas
doaj   +1 more source

Literature and Folklore in the Cid’s Post Mortem Legends

open access: yesMedievalia, 2020
This article focuses on the critical analysis of posthumous legends of el Cid from a multidisciplinary heuristic approach by combining the study of its ancestral folkloric traces with the support of comparatistics in order to appreciate the literary and ...
Alfonso Boix Jovaní
doaj   +1 more source

Tailored Stereo‐Configuration of Crosslinkable Polyester‐Based Solid Polymer Electrolytes for All‐Solid‐State and Binder‐Free Li Metal Batteries

open access: yesAdvanced Science, EarlyView.
Variations in polymer conformations of unsaturated poly(n‐alkyl esters) driven by monomer‐level stereochemistry directly govern Li+ solvation structures in polymer host matrices. The synergistic strategies of polymer conformation control, UV‐induced interchain crosslinking, and end‐group fluorination are implemented for engineering advanced solid ...
Hyun Jun Song   +11 more
wiley   +1 more source

Role of forensic odontologist in post mortem person identification

open access: yesDental Research Journal, 2012
The natural teeth are the most durable organs in the bodies of vertebrates, and humankind′s understanding of their own past and evolution relies heavily upon remnant dental evidence found as fossils.
Jahagirdar B Pramod   +2 more
doaj   +1 more source

Gene Correction Enhances Dopaminergic Cell Therapy in a Nonhuman Primate Model of Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
LRRK2‐mutant induced pluripotent stem cells (iPSCs) were derived from a patient with Parkinson's disease (PD). Using CRISPR/Cas9–mediated gene editing, the pathogenic LRRK2 mutations were precisely corrected, and isogenic dopaminergic neural progenitor cells (DA‐NPCs) were subsequently generated.
Qing Yan   +29 more
wiley   +1 more source

Bipolar Palladium Membrane Enabling Crossover‐Free Selective Proton Transport

open access: yesAdvanced Science, EarlyView.
This study introduces a crossover‐free bipolar palladium membrane that transports protons selectively via reversible Pd/PdHx absorption–desorption and lattice hydrogen diffusion, overcoming the conductivity–selectivity trade‐off of polymer membranes. It enables water‐fed Li‐mediated ammonia synthesis, achieving 51% Faradaic efficiency and stable 12 h ...
Jiyeon Baek   +11 more
wiley   +1 more source

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