Results 71 to 80 of about 5,696,653 (284)

Probing the Energy Landscape of α‐Synuclein Amyloid Fibril Formation by Systematic K‐to‐Q Mutagenesis

open access: yesAdvanced Science, EarlyView.
We use lysine‐to‐glutamine mutations to study the effect of electrostatics on the kinetics and thermodynamics of alpha‐synuclein amyloid fibril formation. We find that mutational effects map on their structural context within fibrils and identify residues that modulate the energy landscape of alpha‐synuclein self‐assembly. Our work outlines a scalable,
Antonin Kunka   +10 more
wiley   +1 more source

Estimation of post- mortem interval by some biochemical changes of vitreous humor.

open access: yesمجله كليه طب الكندي, 2015
Background:No previous Iraqi study was done on the estimation of post mortem interval (PMI) from the medico-legal point of view; depending on the biochemical changes of vitreous humor.Objectives:To find out the relationship between some biochemical ...
Saad Kadhum Kareem
doaj  

Imaging and Artificial Intelligence in Forensic Reconstruction and PMI/PMSI Estimation of Human Remains in Terrestrial and Aquatic Contexts

open access: yesForensic Sciences
The application of advanced imaging techniques, particularly computed tomography (CT), photogrammetric scanning, and three-dimensional reconstructions of body surfaces and skeletal remains, is becoming a crucial component of Forensic Anthropology.
Alessia Leggio   +2 more
doaj   +1 more source

The effects of death and post-mortem cold ischemia on human tissue transcriptomes

open access: yesNature Communications, 2018
RNA levels in post-mortem tissue can differ greatly from those before death. Studying the effect of post-mortem interval on the transcriptome in 36 human tissues, Ferreira et al.
Pedro G. Ferreira   +21 more
doaj   +1 more source

Defect‐Engineered LiYO2 Interlayers Enabling Fast Interfacial Li+ Transport in All‐Solid‐State Batteries

open access: yesAdvanced Science, EarlyView.
Defect‐engineered LiYO2 interlayers are designed through aliovalent Zn2+ and Zr4+ substitution to regulate Li+ point‐defect chemistry in Ni‐rich cathodes. Compared with Li‐excess‐type LYZnO, Li‐vacancy‐type LYZrO enables faster Li+ transport, suppresses Li6PS5Cl decomposition, lowers interfacial resistance, and mitigates polarization growth, thereby ...
Sodam Kim   +6 more
wiley   +1 more source

Algor mortis

open access: yesRevSALUS, 2022
Catarina Lemos
doaj   +1 more source

Adaptive Network Stabilization Despite Profound Structural Reorganization in Human Organotypic Cultures

open access: yesAdvanced Science, EarlyView.
Adult human organotypic cortical slices undergo marked neuronal loss, laminar disruption, and glial activation, yet their network activity progressively stabilizes after a variable period. Electrophysiology, longitudinal calcium imaging, and quantitative histology show that structurally remodeled human circuits show adaptive capacity resulting in ...
Estilla Zsófia Tóth   +20 more
wiley   +1 more source

Smartphone‐Guided Visible Light Modulation of RSNOs for Antimicrobial Activity via Controlled Nitric Oxide Release

open access: yesAdvanced Science, EarlyView.
A light‐activated catheter insert combines antimicrobial blue light with nitric oxide release to generate complementary oxidative and nitrosative stress, producing potent broad‐spectrum antimicrobial activity. The approach achieves greater than 4‐log reductions in bacterial and fungal viability and significantly reduces Staphylococcus aureus ...
Alexander Bruckmann   +7 more
wiley   +1 more source

Characterizing Biopolymer Electrolytes in Zinc–Air Batteries: Challenges, Best Practices, and a Robust Workflow Guiding Future Research Paths

open access: yesAdvanced Energy Materials, EarlyView.
Bio‐based gel polymer electrolytes promise sustainable, mechanically adaptable zinc–air batteries, yet their progress is constrained by inconsistent characterization. This review critically links formulation, structure, interfaces, and cell performance, identifies methodological gaps under alkaline operating conditions, and proposes application ...
Matteo Milanesi   +6 more
wiley   +1 more source

Nanocrystalline LCO/LLZO Composite Cathode Films for Solid State Batteries

open access: yesAdvanced Energy Materials, EarlyView.
A single precursor solution is solution‐deposited and calcined at only 750°C to yield a dense, nanograined LiCoO2/LLZO composite cathode, in which both phases crystallize independently with minimal interdiffusion. Assembled into all‐solid‐state Li‐metal batteries, the composite delivers 111.7 mAh g−1 initial discharge capacity and retains 93% after 100
Lucie Quincke   +8 more
wiley   +1 more source

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