Results 71 to 80 of about 83,899 (293)

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

Advanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes, Xiuqi Ji, Serena Gasperoni, Choham Sudre‐Chinsky, Amirali Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya Narayan, Manfred Uhr, Christian Namendorf, Camilla Bellone, Alon Chen, Felix Hausch, Juan Pablo Lopez, Mathias V. Schmidt   +15 more
wiley   +1 more source

Advancing time-since-interval estimation for clandestine graves: a forensic ecogenomics perspective into burial and translocation timelines using massively parallel sequencing

Frontiers in Microbiology
Forensic taphonomy and entomology has focused on estimating the post-mortem interval (PMI), particularly for surface depositions, using human cadavers and other mammalian models by considering morphological changes of the body and insect activity during ...
Cherene de Bruyn, Cherene de Bruyn, Kirstie Scott, Kirstie Scott, Heather Panter, Heather Panter, Frederic Bezombes, Frederic Bezombes, Komang Ralebitso-Senior, Komang Ralebitso-Senior   +9 more
doaj   +1 more source

CHCHD10 Mitigates Alzheimer's Disease‐Related Phenotypes in Association With Epigenetic Remodeling in Directly Reprogrammed Neurons

Advanced Science, EarlyView.
CHCHD10 loss in Alzheimer's disease is associated with mitochondrial dysfunction, epigenomic disruption, and tau pathology. Restoration of CHCHD10 shifts DNA methylation toward a non‐disease state and reduces tau and amyloid pathology, with KATNAL2 acting as a downstream effector.
Teresa M. Thomas, Ching‐Yao Yang, Kexin Zhang, Liam Wetzel, Dina Bugybayeva, Julia Ferguson, Md Mahmudul Hasan, William Samsa, Nandita Patil, Anshul Dash, Tarini Gowda, Xiongwei Zhu, Feixiong Cheng, Tian Liu   +13 more
wiley   +1 more source

Estimation of post- mortem interval by some biochemical changes of vitreous humor.

مجله كليه طب الكندي, 2015
Background:No previous Iraqi study was done on the estimation of post mortem interval (PMI) from the medico-legal point of view; depending on the biochemical changes of vitreous humor.Objectives:To find out the relationship between some biochemical ...
Saad Kadhum Kareem
doaj  

Imaging and Artificial Intelligence in Forensic Reconstruction and PMI/PMSI Estimation of Human Remains in Terrestrial and Aquatic Contexts

Forensic Sciences
The application of advanced imaging techniques, particularly computed tomography (CT), photogrammetric scanning, and three-dimensional reconstructions of body surfaces and skeletal remains, is becoming a crucial component of Forensic Anthropology.
Alessia Leggio, Ricardo Ortega-Ruiz, Giulia Iacobellis   +2 more
doaj   +1 more source

The effects of death and post-mortem cold ischemia on human tissue transcriptomes

Nature Communications, 2018
RNA levels in post-mortem tissue can differ greatly from those before death. Studying the effect of post-mortem interval on the transcriptome in 36 human tissues, Ferreira et al.
Pedro G. Ferreira, Manuel Muñoz-Aguirre, Ferran Reverter, Caio P. Sá Godinho, Abel Sousa, Alicia Amadoz, Reza Sodaei, Marta R. Hidalgo, Dmitri Pervouchine, Jose Carbonell-Caballero, Ramil Nurtdinov, Alessandra Breschi, Raziel Amador, Patrícia Oliveira, Cankut Çubuk, João Curado, François Aguet, Carla Oliveira, Joaquin Dopazo, Michael Sammeth, Kristin G. Ardlie, Roderic Guigó   +21 more
doaj   +1 more source

A Review of Failure Modes and Safety Strategies of Lithium‐Ion Batteries from Materials to Systems

Advanced Science, EarlyView.
A cascade‐aware framework is presented for lithium‐ion battery safety, linking thermal runaway initiation, acceleration, runaway reaction, and propagation with material‐, cell/pack‐, and system‐level interventions. By integrating failure mechanisms, quantitative safety indicators, and staged interception strategies, this review highlights how safer ...
Jin Hyeok Yang, Jae Yoon Sung, Hyunji Kweon, Seohyun Kim, Byunghoon Kim, Jongsoon Kim, Junyoung Mun, Jung Ho Kim, Ki Jae Kim   +8 more
wiley   +1 more source

Algor mortis

RevSALUS, 2022
Catarina Lemos
doaj   +1 more source

An assessment of the impact of environmental factors on the quality of post-mortem DNA profiling.

, 2009
DNA profiling has ignited public interest and consequently their expectations for the capabilities of forensic criminal and science investigations. The prospect of characterising the genetic makeup of individuals or trace samples from a wide variety of ...
Gunawardane, Dalugama Mudiyanselage Don Dimuth Nilanga
core  

Post-mortem interval comparison in different meat conditions [PDF]

, 2022
Lack of data in different post-mortem interval estimation conditions limit the application of entomological evidence in crime investigation. Therefore, this study investigates the decomposition stages, insect succession patterns, complete life cycle ...
Mohamad, Durratun Nasuha
core