Results 41 to 50 of about 92,874 (250)

What was Killing Babies in Ipswich Between 1872 and 1909?

Historical Life Course Studies, 2022
This paper examines the causes of infant mortality for the port town of Ipswich between 1872 and 1909. Ipswich is the only town in England for which a complete run of computer-readable, individual-level causes of death are available in the late 19th and
Eilidh Garrett, Alice Reid
doaj   +1 more source

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

Advanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu, Cheng Kiu Ho, Jitao Liu, Lei Cui, Yangfeng Hou, Cai Liang, Wenchu Ye, Randolph H. L. Wong, Shohei Hori, Bin Zhou, Kathy O. Lui   +10 more
wiley   +1 more source

Inequalities in mortality of infants under one year of age according to foetal causes and maternal age in rural and urban areas in Poland, 2004–2013

Annals of Agricultural and Environmental Medicine, 2016
Introduction European countries are characterized by low mortality during the infancy period compared to other areas of the world. However, there are significant disparities in the state of infant health which are related to socio-economic conditions and
Agnieszka Genowska, Magdalena Zalewska, Jacek Jamiołkowski, Urszula Stepaniak, Andrzej Szpak, Elżbieta Maciorkowska, Jarosław Pinkas   +6 more
doaj   +1 more source

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

Advanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng, Zhengqiang Wu, Yu Xiong, Zhongya Gao, Yishan Liu, Ziyi Wang, Haibin Wang, Chaofeng Han, Wenxiang Chu, Xuhua Lu   +9 more
wiley   +1 more source

Biomimetic Bone Marrow Monocyte Membrane‐Fused Extracellular Vesicles for Targeted Therapy of Myocardial Infarction

Advanced Science, EarlyView.
This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song, Hao Yang, Qiqi Zhang, Wenqin Zhou, Rui Wang, Yuxing Xie, Emeli Chatterjee, Guoping Li, Jizong Jiang, Qiulian Zhou, Cuimei Zhao   +10 more
wiley   +1 more source

What was Killing Babies in Palma, Spain? Analysing Infant Mortality Patterns Using Individual-Level Cause of Death Data, 1836–1930

Historical Life Course Studies
This paper explores infant mortality patterns to determine the epidemiological profile of the port city of Palma, Spain between 1836 and 1930 using individual-level cause of death and testing the newly constructed ICD10h coding system.
Joana Maria Pujadas-Mora
doaj   +1 more source

A Humanized Anti‐gD Broadly Neutralizing Antibody Confers Complete Post‐Exposure Protection against Pseudorabies Virus

Advanced Science, EarlyView.
Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun, Jianbo Liu, Shi‐Jia Xu, Meng‐Xin Wang, Hongliang Zhang, Yanhe Zhang, Zhi‐Jun Tian, Jin‐Mei Peng, Xin Yin, Tong‐Qing An, Xue‐Hui Cai, Yan‐Dong Tang   +11 more
wiley   +1 more source

Inequalities in early childhood mortality in Myanmar - Association between parents’ socioeconomic status and early childhood mortality

Global Health Action, 2019
Background: Despite global achievements in reducing early childhood mortality, disparities remain. There have been empirical studies of inequalities conducted in low- and middle-income countries.
Sai San Moon Lu, Jennifer Stewart Williams, Johan Nilsson Sommar   +2 more
doaj   +1 more source

Temporal and geographical trends in infant, neonatal and post-neonatal mortality in Italy between 1991 and 2009 [PDF]

Italian Journal of Pediatrics, 2013
Infant mortality is a key indicator of child and population health. The aim of this study is to analyse the trends in infant mortality rates (IMRs) and their components (neonatal mortality rates-NMRs and post-neonatal mortality rates-PNMRs) from 1991 to 2009 both at the national level and across the three Italian large geographical macro-areas (North ...
DALLOLIO, LAURA, LENZI, JACOPO, FANTINI, MARIA PIA   +2 more
openaire   +3 more sources

Hair Follicle Seedling Cryomicroneedles from Hierarchical Microfluidic Organoid on a Chip

Advanced Science, EarlyView.
In this paper, a hierarchical microfluidic chip is developed to produce uniform hair follicle organoids (HFOs) in cryomicroneedles. Cryopreservation agents encapsulate HFOs, preserving viability and hair growth potential. The cryomicroneedles enable simple intradermal transplantation with good skin penetration.
Xinyue Cao, Dongyu Xu, Minhui Lu, Yuanjin Zhao   +3 more
wiley   +1 more source