Results 61 to 70 of about 10,520,983 (276)

Determinant of Attributes and Correlation of Safety Performance via Post Occupancy Evaluation (POE) for Low- Cost Housing

Journal of Design and Built Environment, 2018
The aspects in a completed residence or house should able to enhance the quality of a building as well as to provide safety to the occupants. It has become increasingly important to evaluate housing property for many reasons. The attempt to enhance the aspect of safety planning in developing low cost houses is still neglected and one of the reasons ...
Husrul Nizam Husin, Natasha Khalil, Syahrul Nizam Kamaruzzaman, Abdul Hadi Nawawi, Faridah Ismail   +4 more
openaire   +2 more sources

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

Advanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu, Wanying Xiang, Xinyue Wang, Yue Pan, Jing Gao, Jiezhen Yang, Yufei Wang, Zhipu Zhu, Man Tong, Lei Jin, Yan Ye   +10 more
wiley   +1 more source

Ethics and Professional Practice: Post-Occupancy Accountability in Healthcare Architecture

Proceedings of the International Conference of Contemporary Affairs in Architecture and Urbanism-ICCAUA
This research examines the ethical obligations of architects after project handover, using the Post-Occupancy Evaluation (POE) model in healthcare architecture in Bahrain.
Mashael Hisham AlDoy
doaj   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Post-Occupancy Evaluation and Design Quality in Brazil: Concepts, Approaches and an Example of Application

Gestão & Tecnologia de Projetos, 2010
This article aims to describe the origins and evolution of post-occupancy evaluation (POE) activities in Brazil. This methodology was consolidated in the Brazilian academic field in the mid-1990s.
Sheila Waber Ornstein, Rosaria Ono
doaj   +1 more source

From Sensing Mechanisms to System Co‐Design: Graphene‐Based Sensors and Readout Circuits

Advanced Science, EarlyView.
This review establishes a unified PS–EQ–RF framework linking graphene sensing mechanisms, native electrical outputs, and output‐specific readout circuits. Voltage‐, current‐, resistance‐, and capacitance‐type sensing systems are systematically classified to guide architecture selection, low‐noise design, system co‐design, and practical integration ...
Jinduo Zhang, Meng Chen, Guanchen Li, Ruifeng Liu, Yingxin Wang, Ziran Zhao   +5 more
wiley   +1 more source

Structural Basis of Shiga Toxin Neutralization by Human Antibodies Targeting Canonical Receptor‐Binding and Non‐Canonical Assembly Sites

Advanced Science, EarlyView.
Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke, Xin Li, Xiaoli Wang, Zhaoxia Huang, Shaojie Xue, Yuyang Liu, Jing Pan, Guowei Hu, Yayu Wang, Cheng Wang, Shoudeng Chen   +10 more
wiley   +1 more source

An innovative approach to post-occupancy evaluation of architectural heritages in the Peking-Mukden railway

Heritage Science
The architectural heritages of the Peking-Mukden Railway has witnessed the industrialization of China. When it no longer serves its original function, finding a new way for reuse becomes a trend.
Fuying Liu, Zuliang Lu, Wei Qiang
doaj   +1 more source

FOXP1 Knockdown Reprograms Th9 CAR‐T Cells to Overcome Antigen Escape

Advanced Science, EarlyView.
FOXP1 knockdown enhances Th9 CAR‐T cell function by promoting IL‐9 production, effector activation, and reduced exhaustion. Reprogrammed Th9 CAR‐T cells strengthen direct tumor killing and activate endogenous antitumor immunity through dendritic cells and CD8+ T cells, thereby suppressing both antigen‐positive and antigen‐loss tumor growth and ...
Yihan Zhu, Xingwei Xie, Xiaohuan Wu, Suidong Ouyang, Yang Zhou, Kang Wen, Yutong Zhong, Yuyang Chen, Handuo Wang, Yuan Gao, Ling Jiang, Hui Li, Wenli Zhao, Abai Xu, Enguang Bi   +14 more
wiley   +1 more source

Research on Post-Use Evaluation of Community Green Space Rectification Based on a Multi-Dimensional Perception System: A Case Study of Jiayuan Sanli Community in Beijing

Land
Community green spaces (CGSs) constitute a crucial element of urban land use, playing a pivotal role in maintaining the stability of urban ecosystems and enhancing the overall quality of the urban environment.
Meng Li, Jian Zhang, Yuchen Wang
doaj   +1 more source