Results 121 to 130 of about 6,574,666 (302)

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

FLIP: A Novel Feedback Learning-Based Intelligent Plugin Towards Accuracy Enhancement of Chinese OCR

Mathematics
Chinese Optical Character Recognition (OCR) technology is essential for digital transformation in Chinese regions, enabling automated document processing across various applications. However, Chinese OCR systems struggle with visually similar characters,
Xinyue Tao, Yueyue Han, Yakai Jin, Yunzhi Wu   +3 more
doaj   +1 more source

Other title: Annual report of the Legislative Post Audit Committee and Legislative Division of Post Audit, fiscal year 1994

, 1995
Fiscal year ends June 30.; "January 10, 1995."Constitutes the annual report of the ...
Kansas. Legislative Post Audit Committee.
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Novel Physics-Informed Bayesian Fusion Post-Processor for Enhanced Gait Phase Recognition Using Surface Electromyography

IEEE Transactions on Neural Systems and Rehabilitation Engineering
Myoelectric pattern recognition systems serve as a promising predictive control approach for the lower limbs prostheses and exoskeletons. However, their actual deployment is challenged by the signal stochastic nature that could contaminate the decision ...
Rami Mobarak, Alessandro Mengarelli, Rami N. Khushaba, Ali H. Al-Timemy, Federica Verdini, Sandro Fioretti, Laura Burattini, Andrea Tigrini   +7 more
doaj   +1 more source

Other title: Annual report of the Legislative Post Audit Committee and Legislative Division of Post Audit, fiscal year 1995

, 1995
Fiscal year ends June 30.; "October 23, 1995."Constitutes the annual report of the ...
Kansas. Legislative Post Audit Committee.
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Effect of Post-Processing on the Microstructure of WE43 Magnesium Alloy Fabricated by Laser Powder Directed Energy Deposition

Journal of Manufacturing and Materials Processing
Additive manufacturing of magnesium (Mg) alloys is of interest for the fabrication of complex-shaped lightweight materials. This study evaluates the microstructure of WE43 Mg alloy deposited using laser powder directed energy deposition (LPDED) additive ...
Leila Sorkhi, Nathan J. Madden, Grant A. Crawford   +2 more
doaj   +1 more source

Meat processing plants : determining what factors may have contributed to a decline in the number of small plants and what impact that has had on the state's economy

, 2002
Cover title.; "A report to the Legislative Post Audit Committee".; "November 2002"
Murdie, Laurel.
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source