Results 101 to 110 of about 411,630 (328)

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Epidemiology and treatment of post-stroke depression

Neuropsychiatric Disease and Treatment, 2008
Stefano PaolucciFondazione Santa Lucia – I.R.C.C.S, Rome, ItalyAbstract: Mood depression is a common and serious complication after stroke. According to epidemiological studies, nearly 30% of stroke patients develop depression, either in the ...
Stefano Paolucci
doaj  

Prevalence of depression in post-stroke aphasia: systematic review and meta-analysis

BMC Neurology
Background Depression is a significant consequence of post-stroke aphasia, adversely affecting quality of life; however, its frequency remains unclear. The objective of this systematic review and meta-analysis is to quantify depression prevalence rates ...
Amy Vogel-Eyny, Ye-Jee Jung, JungMoon Hyun, Eleanor Siegle, Aisha Haroun, Samsun Nahar, Sarah Sarkas, Stewart A. Shankman, Samantha Slattery, Sameer Ashaie   +9 more
doaj   +1 more source

Cerebral small vessel disease burden is associated with poststroke depressive symptoms: A 15-month prospective study [PDF]

, 2018
Objective: All types of cerebral small vessel disease (SVD) markers including lacune, white matter hyperintensities (WMH), cerebral microbleeds, and perivascular spaces were found to be associated with poststroke depressive symptoms (PDS).
De-Feng Wang, Gabor S. Ungvari, Hee-Ju Kang, Vincent Chung-Tong Mok, Wai-Kwong Tang, Wai-Kwong Tang, Winnie Chiu-Wing Chu, Yan Liang, Yang-Kun Chen   +8 more
core   +3 more sources

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

Advanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu, Jia‐Rui Bi, Zong‐Yan Yu, Meng Tian, Zhi‐Yue Chen, Ran Wei, Miao‐Miao Wang, Hai‐Wei Zha, Yu‐Qing Zhang, Hong‐Jing Wang, Bang‐You Qiang, Shuang‐Shuang Sun, Xiao‐Juan Zhu, Wen‐Bing Chen, Dong Sun   +14 more
wiley   +1 more source

Bibliometric analysis of depression in post-stroke patients

International Journal of Emergency Medicine
Introduction Stroke is a life-threatening condition that increasingly damages cerebral tissue over time and can lead to serious post-effects, including depression, which can hinder a patient’s recovery from stroke and reduce quality of life.
Dehao Zheng, Sydney Vaughn, Murdoc Gould, Latha Ganti   +3 more
doaj   +1 more source

Regenerative medicine: Stroke survivor and carer views and motivations towards a proposed stem cell clinical trial using placebo neurosurgery [PDF]

, 2018
Background  Few studies explore stroke survivor views and motivations towards stem cell therapy (SCT). This qualitative study explores the views and motivations of both stroke survivors and their partners/carers towards a proposed 2-arm Phase III ...
Abhyankar, Abhyankar, Abhyankar, Aked, Akinsanya, Alaszewski, Alfred, Anderson, Bekker, Bell, Bowling, Braun, Brown, Campbell, Connell, Coolbrandt, Dekkers, Dixon-Woods, Donovan, Donovan, Donovan, Donovan, Entwhistle, Exel, Gillies, Goetz, Greenwood, Guba, Guest, Illingworth, Juraskova, King, Knebly, Lidz, Liu, Lo, Luker, Madse, McCann, McDonald, Miles, Mills, Moorcraft, Paolucci, Rigby, Ritchie, Robinson, Sagi, Savitz, Secrest, Sinden, Singer, Stroke Association, Swift, Treweek, Welton, West, World Medical Association   +57 more
core   +3 more sources

Post-Stroke Depressive Symptoms Are Associated with Post-Stroke Characteristics [PDF]

Cerebrovascular Diseases, 2009
<i>Background:</i> Several studies have described the frequency and risk factors of post-stroke depressive symptoms (PSDS). However, most studies did not exclude patients with depressive symptoms shortly <i>before</i> stroke and paid little attention to prestroke risk factors of depression, including previous depressive episodes,
Snaphaan, L.J.A.E., Snaphaan, L.J.A.E., Snaphaan, L.J.A.E., van der Werf, S.P., Kanselaar, K., de Leeuw, H.F.   +5 more
openaire   +3 more sources

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

Advanced Science, EarlyView.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du, Rui Deng, Ya Wu, Hong‐Xia Ren, Zong‐Hong Lin, Yang‐Bao Miao   +5 more
wiley   +1 more source

Depression and functional disability in stroke patients

Journal of Public Health Research, 2020
Background: Stroke patients often suffer from depression, a mental disorder that worsens their condition and slows down the recovery process. Depression is the leading cause of functional disability due to inability to cope with daily stressors and to ...
Puji Astuti, Kusnanto , Ferra Dwi Novitasari   +2 more
doaj   +1 more source