Results 111 to 120 of about 411,630 (328)

Home Care Holistic on the Change of Anxiety and Depression for the Patient with Stroke Ischemic [PDF]

, 2012
Introduction: Stroke is the main cause of long-term disability. It was reported that one third out of stroke survivors showed dementia in three months after stroke.
Krisnawati, K. (Krisnawati), Widarti, L. (Luluk)   +1 more
core  

A systematic review of recommended modifications of CBT for people with cognitive impairments following brain injury [PDF]

, 2019
Due to diverse cognitive, emotional and interpersonal changes that can follow brain injury, psychological therapies often need to be adapted to suit the complex needs of this population.
Gallagher, Melanie, McLeod, Hamish J., McMillan, Thomas M.   +2 more
core   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Post-Stroke Depression: Focus on Diagnosis and Management during Stroke Rehabilitation [PDF]

, 2007
Post-Stroke Depression: Focus on Diagnosis and Management during Stroke Rehabilitation. Geriatrics & Aging.
Bakas, Tamilyn, Johnson, Elizabeth A, Williams, Linda S.   +2 more
core  

Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery. [PDF]

, 2011
BACKGROUND: Stroke is the major cause of adult disability. Selective serotonin reuptake inhibitors (SSRIs) have been used for many years to manage depression.
Anne Claxton, Cheng-Fang Hsieh, Gillian E Mead, Graeme J Hankey, Mansur A Kutlubaev, Maree L Hackett, Rebecca Lee   +6 more
core   +1 more source

The Role of Ionic Liquids at the Biological Interfaces in Bioelectronics

Advanced Science, EarlyView.
Ionic liquids (ILs) are highlighted as key artificial ionic materials that bridge biological ion‐based signaling and electronic devices. By understanding their composition, structure, function relationships, and mechanisms, ILs can advance from high performance electrolyte to core materials enabling integrated, multifunctional bioelectronics for ...
Yeong‐sinn Ye, Young Jin Jo, Ji Yeon Oh, Ju Yeon Jeong, Lili Guo, Tae‐il Kim   +5 more
wiley   +1 more source

Exploring the occurence and risk factors of post-stroke depression among stroke survivors in Africa: a comprehensive systematic review and meta-analysis

BMC Public Health
Background Post-stroke depression is a significant health concern, especially in developing countries. The high prevalence, incidence, and complexity of depression among stroke survivors pose a substantial occurence on vulnerable individuals.
Techilo Tinsae, Wondale Getinet, Setegn Fentahun, Shegaye Shumet, Girmaw Medifu, Fantahun Andualem, Girum Nakie, Tesfaye Segon, Selam Koye, Gebresilassie Tadesse, Gidey Rtbey   +10 more
doaj   +1 more source

Neuropathological substrates and structural changes in late-life depression: the impact of vascular burden [PDF]

, 2018
A first episode of depression after 65years of age has long been associated with both severe macrovascular and small microvascular pathology. Among the three more frequent forms of depression in old age, post-stroke depression has been associated with an
Bouras, Constantin, Giannakopoulos, Panteleimon, Hof, Patrick, Kövari, Eniko, Santos, Micaela, Xekardaki, Aikaterini   +5 more
core  

Variations in follow-up services after inpatient stroke rehabilitation: A multicentre study [PDF]

, 2009
Background: Care after discharge from inpatient stroke rehabilitation units varies across Europe. The aim of this study was to compare service delivery after discharge.
Baert, Ilse, Brinkmann, Nadine, De Weerdt, Willy, De Wit, Liesbet, Dejaeger, Eddy, Feys, Hilde, Jenni, Walter, Kaske, Christiane, Leys, Mark, Lincoln, Nadina, Louckx, Fred, Putman, Koen, Schuback, Birgit, Schupp, Wilfried, Smith, Bozena   +14 more
core   +2 more sources

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source