Results 211 to 220 of about 411,630 (328)

In Vivo Mapping of Catecholaminergic Loss and Iron Deposition in Huntington's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background The pathophysiology of Huntington's disease (HD) remains obscure. Magnetic resonance imaging (MRI) can reveal in vivo molecular changes related to disease pathology. Objectives To investigate catecholaminergic neuronal integrity and subcortical brain iron accumulation in HD employing neuromelanin‐sensitive MRI, and quantitative ...
Edoardo R. de Natale   +11 more
wiley   +1 more source

Rehabilitation paired with vagus nerve stimulation for motor function of chronic ischemic stroke patients in China: Study protocol of a multicenter randomized controlled trial (Repair Study)

open access: yesNeuroprotection, EarlyView.
Mechanism of vagus nerve stimulation (VNS) paired with movement: VNS activates cholinergic nucleus basalis and noradrenergic locus coeruleus neurons, modulating motor cortex activity (light green and red areas) in a task‐specific manner during targeted movements. VNS: vagus nerve stimulation.
Anchao Yang   +56 more
wiley   +1 more source

How does Frailty Impact Peri‐Operative and Speech Recognition Outcomes for Cochlear Implants in Veterans?

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To investigate the association of frailty with post‐cochlear implant (CI) admission, morbidity, and CI‐aided word recognition outcomes in veterans. Study Design Retrospective cohort. Setting Single‐institution tertiary care Veterans Health Administration (VHA) hospital.
Kaitlyn A. Brooks   +4 more
wiley   +1 more source

The ketogenic diet alters microbiome‐metabolome profiles to improve West syndrome therapy

open access: yesPediatric Investigation, EarlyView.
The ketogenic diet alleviates West syndrome by reshaping gut microbiota (increasing Bacteroides, Parabacteroides, and reducing Escherichia and Bifidobacterium), and modulating metabolites—including anticonvulsant lipids (e.g., capric acid), suppressed harmful lipids (e.g., 2‐methylbutyroylcarnitine), and amino acids and analogs (e.g., 3‐sulfinoalanine)—
Gan Xie   +5 more
wiley   +1 more source

Group rehabilitation for adults with acquired neurological disorders: A systematic review of mono‐ and interdisciplinary interventions in physical and speech‐language therapy

open access: yesPM&R, EarlyView.
Abstract Background Group treatments and interdisciplinary collaboration are recommended in evidence‐based guidelines for neurorehabilitation, including physical and speech‐language therapy. Evidence suggests that activating overlapping neural networks for upper extremity motor control and speech‐language processing produces synergistic effects during ...
Nina Greiner   +3 more
wiley   +1 more source

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