Results 171 to 180 of about 213,229 (323)
Evidence-based pharmacological treatment of anxiety disorders, post-traumatic stress disorder and obsessive-compulsive disorder: A revision of the 2005 guidelines from the British Association for Psychopharmacology
Journal of Psychopharmacology, 2014 D. Baldwin, I. Anderson, D. Nutt, C. Allgulander, B. Bandelow, J. D. den Boer, D. Christmas, S. Davies, N. Fineberg, Nicky Lidbetter, A. Malizia, P. McCrone, D. Nabarro, C. O'Neill, Jan Scott, N. J. van der Wee, H. Wittchen +16 moresemanticscholar +1 more sourceDisrupting CSPG‐Driven Microglia–Astrocyte Crosstalk Enables Scar‐Free Repair in Spinal Cord Injury
Advanced Science, EarlyView.This study identifies CSPGs as key drivers of glial scar maturation after spinal cord injury by reprogramming microglial metabolism and inducing astrocyte fibrosis. To address this, a reactive oxygen species‐responsive, reactive astrocyte‐targeted ChABC gene delivery system is designed to locally degrade CSPGs, precisely disrupt maladaptive glial ...Yufei Zheng, Zhaowei Zhang, Zezhou Fu, Qingqing Wang, Siwen Zhang, Tingyu Zhang, Meifei Zhu, Shunwu Fan, Youqing Shen, Jiajia Xiang, Xin Liu +10 morewiley +1 more sourceCRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis
Advanced Science, EarlyView.This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...Yangyang Shi, Fudong Li, Tianyi Zhao, Kaiqiang Sun, Danying Zhang, Chen Yan, Ximing Xu, Jingchuang Sun, Xulin Hu, Xin Yong, Jiangang Shi, Yuan Wang +11 morewiley +1 more sourceGenome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder
Nature GeneticsC. Nievergelt, A. Maihofer, Elizabeth G. Atkinson, Chia-Yen Chen, Karmel W. Choi, Jonathan R. I. Coleman, N. Daskalakis, Laramie E. Duncan, R. Polimanti, Cindy Aaronson, A. Amstadter, Soren B. Andersen, O. Andreassen, P. Arbisi, A. Ashley-Koch, S. Austin, E. Avdibegović, Dragan Babić, S. Bacanu, D. Baker, Anthony K. Batzler, Jean C. Beckham, S. Belangero, C. Benjet, C. Bergner, L. Bierer, J. Biernacka, L. Bierut, Jonathan I Bisson, M. Boks, Elizabeth A. Bolger, Amber M. Brandolino, G. Breen, R. Bressan, Richard A. Bryant, A. Bustamante, J. Bybjerg-Grauholm, Marie Bækvad-Hansen, A. Børglum, S. Børte, L. Cahn, Joseph R. Calabrese, J. Caldas-de-Almeida, Chris Chatzinakos, Sheraz Y. Cheema, Sean A. P. Clouston, L. Colodro-Conde, Brandon J. Coombes, C. S. Cruz-Fuentes, A. Dale, S. Dalvie, Lea K. Davis, J. Deckert, D. Delahanty, Michelle F. Dennis, F. Désarnaud, Christopher P. DiPietro, S. Disner, A. Docherty, Katharina Domschke, G. Dyb, A. Kulenović, H. Edenberg, Alexandra Evans, Chiara Fabbri, Negar Fani, Lindsay A. Farrer, A. Feder, N. Feeny, J. Flory, David Forbes, C. Franz, Sandro Galea, M. Garrett, B. Gelaye, J. Gelernter, E. Geuze, Charles F. Gillespie, S. Goleva, S. Gordon, Aferdita Goçi, L. Grasser, Camila Guindalini, Magali Haas, S. Hagenaars, Michael A. Hauser, A. Heath, S. Hemmings, V. Hesselbrock, I. Hickie, Kelleigh Hogan, D. Hougaard, Hailiang Huang, Laura M. Huckins, K. Hveem, M. Jakovljević, Arash Javanbakht, Gregory D. Jenkins, Jessica S. Johnson, Ian R. Jones, T. Jovanovic, Karen-Inge Karstoft, M. Kaufman, J. Kennedy, Ronald C. Kessler, Alaptagin Khan, N. Kimbrel, Anthony P. King, N. Koen, Roman Kotov, H. Kranzler, Kristi Krebs, W. Kremen, P. Kuan, B. Lawford, L. Lebois, Kelli Lehto, D. Levey, Catrin E Lewis, Israel Liberzon, S. Linnstaedt, MarkW. Logue, Adriana Lori, Yi Lu, B. Luft, Michelle K. Lupton, J. Luykx, I. Makotkine, J. Maples-Keller, S. Marchese, Charles Marmar, Nicholas G. Martin, G. Martínez-Levy, K. McAloney, Alexander McFarlane, Katie A McLaughlin, S. McLean, S. Medland, Divya Mehta, Jacquelyn Meyers, V. Michopoulos, Elizabeth A. Mikita, L. Milani, William Milberg, Mark W. Miller, R. Morey, C. P. Morris, Ole Mors, P. Mortensen, M. Mufford, E. Nelson, M. Nordentoft, Sonya B. Norman, Nicole R. Nugent, M. O'Donnell, Holly K Orcutt, P. Pan, M. Panizzon, Gita A. Pathak, Edward S. Peters, Alan L. Peterson, Matthew Peverill, Robert H Pietrzak, Melissa A. Polusny, B. Porjesz, A. Powers, Xue J. Qin, A. Ratanatharathorn, V. Risbrough, Andrea L. Roberts, Alex O. Rothbaum, B. Rothbaum, Peter Roy-Byrne, Kenneth J. Ruggiero, A. Rung, H. Runz, Bart P F Rutten, Stacey Subbie-Saenz de Viteri, Giovanni Salum, Laura A Sampson, S. Sanchez, Marcos L. Santoro, Carina Seah, S. Seedat, Julia S Seng, A. Shabalin, Christina M. Sheerin, D. Silove, Alicia K. Smith, J. Smoller, S. Sponheim, D. Stein, S. Stensland, Jennifer S Stevens, J. A. Sumner, Martin H Teicher, Wesley K. Thompson, A. Tiwari, Edward Trapido, Monica Uddin, R. Ursano, U. Valdimarsdóttir, Miranda Van Hooff, E. Vermetten, C. Vinkers, J. Voisey, Yunpeng Wang, Zhewu Wang, M. Waszczuk, H. Weber, Frank R Wendt, T. Werge, Michelle A. Williams, Douglas E. Williamson, B. Winsvold, S. Winternitz, Christiane Wolf, Erika J. Wolf, Yan Xia, Ying Xiong, Rachel Yehuda, Keith A. Young, R. M. Young, Clement C. Zai, G. Zai, M. Zervas, Hongyu Zhao, Lori A. Zoellner, J. Zwart, T. deRoon-Cassini, S. V. van Rooij, L. L. van den Heuvel, Murray B. Stein, Kerry Ressler, K. Koenen +234 moresemanticscholar +1 more sourceEarly Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles
Advanced Science, EarlyView.A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT
Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...Xiaoping Xie, Songqi Bi, Bang Su, Rongqi Zhou, Xudong Li, Zhixing Yan, Xiaoyang Zhou, Fanxu Wang, Tiecheng Yu +8 morewiley +1 more source