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Sex and menopause-based differences in presentation of early Lyme disease: A prospective cohort study. [PDF]

Clin Exp Med
Rebman AW, Yang T, Aucott JN.
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A Review of Post-treatment Lyme Disease Syndrome and Chronic Lyme Disease for the Practicing Immunologist

Clinical Reviews in Allergy and Immunology, 2021
Lyme disease is an infection caused by Borrelia burgdorferi sensu lato, which is transmitted to humans through the bite of an infected Ixodes tick. The majority of patients recover without complications with antibiotic therapy. However, for a minority of patients, accompanying non-specific symptoms can persist for months following completion of therapy.
Katelyn H Wong, Eugene D Shapiro
exaly   +3 more sources

Risk of post-treatment Lyme disease in patients with ideally-treated early Lyme disease: A prospective cohort study. [PDF]

International Journal of Infectious Diseases, 2022
Post-treatment Lyme disease (PTLD) is characterized by patient-reported symptoms after treatment for Borrelia burgdorferi infection. The primary aim of this study was to assess whether participants with a history of Lyme disease (LD) would be more likely to meet criteria for PTLD than those without a history of LD.We conducted a longitudinal ...
John N Aucott, Steven A Geller
exaly   +4 more sources

Lyme disease and post-treatment Lyme disease syndrome: the neglected disease in our own backyard

Public Health, 2014
A survey was developed to assess experience and opinions about Lyme disease and post-treatment Lyme disease syndrome (PTLDS) among faculties in public health. No previous surveys of public health faculties have been found in the literature.This is a cross sectional study of public health school faculty members designed to measure knowledge and ...
Eric R Weinstein, John N Aucott
exaly   +3 more sources

Autoantibodies in post-treatment Lyme disease and association with clinical symptoms

Clinical and Experimental Rheumatology, 2023
Autoantibodies have been described in the post-infectious state, specifically after Lyme disease and COVID-19. We aimed to describe the prevalence and potential clinical utility of several commercially available autoantibodies after these infections.Euroimmun panels (myositis, scleroderma and ANA5) were assayed using sera from patients with Lyme ...
Marzieh, Keshtkarjahromi, Alison W, Rebman, Annukka A R, Antar, Yukari C, Manabe, Laura, Gutierrez-Alamillo, Livia A, Casciola-Rosen, John N, Aucott, John B, Miller   +7 more
openaire   +2 more sources

Development of a foundation for a case definition of post-treatment Lyme disease syndrome [PDF]

International Journal of Infectious Diseases, 2013
The study objective is to demonstrate the clinical and research utility of an operationalized definition of post-treatment Lyme disease syndrome (PTLDS), as proposed by the Infectious Diseases Society of America.Seventy-four patients with confirmed erythema migrans and 14 controls were enrolled.
John N Aucott, Lauren A Crowder
exaly   +3 more sources

Pediatric Lyme disease: systematic assessment of post-treatment symptoms and quality of life

Pediatric Research, 2023
Lyme disease is common among children and adolescents. Antibiotic treatment is effective, yet some patients report persistent symptoms following treatment, with or without functional impairment. This study characterized long-term outcome of pediatric patients with Lyme disease and evaluated the case definition of post-treatment Lyme disease (PTLD ...
Maureen, Monaghan, Stephanie, Norman, Marcin, Gierdalski, Adriana, Marques, James E, Bost, Roberta L, DeBiasi   +5 more
openaire   +2 more sources

Audiologic Manifestations of Patients with Post-Treatment Lyme Disease Syndrome

Ear & Hearing, 2003
The purpose of this study was to characterize auditory function in patients diagnosed with post-treatment Lyme disease syndrome (PTLDS).Eighteen patients with PTLDS were evaluated and compared to a normal population. Evaluations consisted of pure tone and speech thresholds, word recognition (WRS), acoustic immittance battery, auditory brain stem ...
Lawrence I, Shotland, Mary Ann, Mastrioanni, Daniel L, Choo, Yvonne M, Szymko-Bennett, Leonard G, Dally, Anita T, Pikus, Kathryn, Sledjeski, Adriana, Marques   +7 more
openaire   +2 more sources

Controlled Trials of Antibiotic Treatment in Patients with Post-Treatment Chronic Lyme Disease

Vector-Borne and Zoonotic Diseases, 2002
Some patients have persistence of profound fatigue, myalgias, arthralgias without arthritis, dysesthesia/paresthesia, and mood and memory disturbances after standard courses of antibiotic treatment for Lyme disease. This constellation of symptoms has been variously referred to as "chronic Lyme disease," "post-Lyme disease syndrome," and "post-treatment
Mark S Klempner
exaly   +3 more sources

Cognitive function in post-treatment Lyme disease Do additional antibiotics help?

Neurology, 2003
It is controversial whether additional antibiotic treatment will improve cognitive function in patients with post-treatment chronic Lyme disease (PTCLD).To determine whether antibiotic therapy improves cognitive function in two randomized double-blind placebo-controlled studies of patients with PTCLD.A total of 129 patients with a physician-documented ...
R F, Kaplan, R P, Trevino, G M, Johnson, L, Levy, R, Dornbush, L T, Hu, J, Evans, A, Weinstein, C H, Schmid, M S, Klempner   +9 more
openaire   +2 more sources