Results 151 to 160 of about 10,116,795 (305)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Faculty salaries in Kansas and the resources committed to pay them

, 1988
"A Report to the Legislative Post Audit Committee by the Legislative Division of Post Audit, State of Kansas"--Cover.; "September 1988" ...
Hafner, Leo M.
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PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Other title: Legislative Coordinating Council; Other title: Legislative Educational Planning Committee; Other title: Legislative Research Department; Other title: Office of the Revisor of Statutes; Other title: Legislative Division of Post Audit

, 1990
application/pdf; October 1990.; Volume numbers and date taken from Kansas Legislative Division of Post Audit website.; "The period covered by this audit was the fiscal year ended June 30, 1989" ...
Tongier, Randy.
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Swedish Consensus Recommendation for Follow-Up After ICU Stay. [PDF]

Acta Anaesthesiol Scand
Åkerman E, Schandl A, Ringdal M, Dahl O, Orwelius L.   +4 more
europepmc   +1 more source

Corrections Ombudsman's Office

, 1987
"A Report to the Legislative Post Audit Committee by the Legislative Division of Post Audit, State of Kansas"--Cover.; "June 1987" ...
Green, Ron (Ronald J.)
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Investigation of Torque Teno Virus Loads as a Marker of Immunosuppression in Pediatric Chronic Renal Failure: A Pilot Study. [PDF]

Pediatr Transplant
Kelly E, Awan A, Wildes D, De Gascun CF, Drew RJ, Heggenstaller A, Riordan M, Hassan J.   +7 more
europepmc   +1 more source

Milford Fish Hatchery

, 1987
"A report to the Legislative Post Audit Committee by the Legislative Division of Post Audit, State of Kansas."--Cover.; "October 1987 ...
Racine, Trudy A.
core