Results 61 to 70 of about 4,701,827 (268)

The formalization of the process of servicing trucks at processing points with several stations

Avtomobilʹnyj Transport (Harʹkov)
Problem. Today, processing points play a crucial role in the operation of supply chains. The efficiency of such points depends on many factors, including the timeliness of logistics operations, the cost characteristics of such services, and the ...
Fedorov Vitalii, Kovtsur Kateryna
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja, Anuja Sule, Katie Ann McMullen, Aditi Dhir, Matthew D. Hall, Heather J. McCrea, Sakir Humayun Gultekin, Mustafa Tekin, Bradley Gampel   +8 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Duchowość monastyczna św. Ambrożego

Vox Patrum, 1998
L'apporto principale di sant'Ambrogio al tema consiste nell'aver inaugurato nel mondo latino la connessione della verginita eon la vita comunitaria, anziche concepirla come scelta individuale, cosicche lo scritto assume i caratteri di regola di vita ...
Bazyli Degórski
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Confronting Post-Traumatic Stress Disorder: Towards the Integration of Psychotherapy and Educational Support [PDF]

مجلة ابحاث كلية التربية الاساسية
This research clarifies the meaning of the phrase post-traumatic stress disorder (PTSD) and the critical importance of understanding this psychological disorder that may result from exposure to a variety of painful and traumatic events, by analyzing the ...
Taha Taha, Mohammad Hussein, Raad Amir, Habib Al Bayati   +3 more
doaj   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Assessment of various post systems' Fracture resistance after endodontic treatment

Journal of Pharmacy and Bioallied Sciences
Objectives: The study's objective is to evaluate the fracture resistance of a tooth that has had endodontic treatment and has been rebuilt using various post and core systems.
Sanjit Kumar Sahoo, Vaibhav Awinashe, Manisha Bhati, Prajakta Ganesh Chougule, Mohammed Ibrahim Mathar, Toby Thomas, Ruchi Garg   +6 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source