Results 161 to 170 of about 897,087 (262)

Foslevodopa/Foscarbidopa in Younger Patients Earlier Within Advanced Parkinson's Disease: Post Hoc Analysis of a Randomized Trial. [PDF]

Neurol Ther
Antonini A, Bergmans B, Kern DS, Gandor F, Nishikawa N, Standaert DG, Fritz B, Gupta R, Nozaki T, Shah MB, Bergmann L, Kimber T.   +11 more
europepmc   +1 more source

Light‐Responsive Enzyme‐Loaded Nanoparticles for Tunable Adhesion and Mechanical Wound Contraction

Advanced Functional Materials, EarlyView.
This study presents a photoactivatable enzyme‐loaded mesoporous nanoparticle system (MPDA_PaTy) that enables light‐triggered tunable tissue adhesion and facilitates mechanical wound contraction. Controlled enzymatic crosslinking at tissue or hydrogel interfaces allows on‐demand adhesion.
Junghyeon Ko, Hyeon‐Jin Kim, Jeong‐Uk Kim, Seh Ri Oh, Tae Hoon Kang, Junghwan Byun, Uk‐Jae Lee, Minglin Ma, Su‐Hwan Kim, Byung‐Gee Kim, Nathaniel S. Hwang   +10 more
wiley   +1 more source

Advanced ampullary cancer: post-hoc analysis of the ABC-01, ABC-02, and ABC-03 clinical trials. [PDF]

Oncologist
Lamarca A, Ross P, Wasan HS, Hubner RA, McNamara MG, Lopes A, Palmer D, Valle JW, Bridgewater J.   +8 more
europepmc   +1 more source

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source

Impact of multidomain lifestyle intervention on dynamics of cognitive frailty: post hoc analysis of the FINGER trial. [PDF]

J Gerontol A Biol Sci Med Sci
Pöyhönen J, Roitto HM, Lehtisalo J, Levälahti E, Strandberg T, Kivipelto M, Kulmala J, Antikainen R, Soininen H, Tuomilehto J, Laatikainen T, Ngandu T.   +11 more
europepmc   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Laser‐Based Sculpturing of Embedded Ultrathin Metal‐Oxide Nanopores for Enhanced Biomolecular Sensing

Advanced Functional Materials, EarlyView.
Controlled laser‐drilling of embedded HfO2 membranes creates three layer nanopores with Gaussian‐shaped cavities sculptured in the supporting layers. These embedded solid‐state nanopores slow DNA translocation by 12‐fold compared to SiNx pores, enabling high‐resolution, label‐free detection of short DNAs, RNAs, and proteins.
Jostine Joby, Yulia Marom, Guocong Lin, Aleksandra Baron‐Wiechec, Amit Meller   +4 more
wiley   +1 more source

Outcomes in participants switching from FVIII replacement therapy to efanesoctocog alfa prophylaxis in XTEND-1: a post hoc analysis. [PDF]

Ther Adv Hematol
Susen S, Kulkarni R, Nogami K, Peyvandi F, Konkle B, Santagostino E, Khan U, Willemze A, Bystrická L, Dumont J, Chowdary P.   +10 more
europepmc   +1 more source

Response to duloxetine in patients with knee pain due to osteoarthritis: an exploratory post hoc analysis of a Japanese Phase III randomized study

, 2018
Naohiro Itoh, Toshinaga Tsuji, Mitsuhiro Ishida, Toshimitsu Ochiai, Shin‐ichi Konno, Yuji Uchio   +5 more
openalex   +2 more sources

Digital Discovery of Synthesizable Metal−Organic Frameworks via Molecular Dynamics‑Informed, High‑Fidelity Deep Learning

Advanced Functional Materials, EarlyView.
Tabular foundation model interrogates the synthetic likelihood of metal−organic frameworks. Abstract Metal–organic frameworks (MOFs) are celebrated for their chemical and structural versatility, and in‑silico screening has significantly accelerated their discovery; yet most hypothetical MOFs (hMOFs) never reach the bench because their synthetic ...
Xiaoyu Wu, Rui Zheng, Quan Liu, Jianwen Jiang   +3 more
wiley   +1 more source