Results 131 to 140 of about 88,248 (294)

From Uncertainty to Pathogenicity: Resolving a CSF1R Variant of Uncertain Significance Using Long‐Read Transcriptomics

Movement Disorders, EarlyView.
Abstract Background CSF1R‐related disorder (CSF1R‐RD) is a severe autosomal dominant leukoencephalopathy characterized by progressive cognitive, neuropsychiatric, and motor decline. Although genetic testing is widely available, numerous likely pathogenic variants in CSF1R frequently remain classified as variants of uncertain significance (VUS ...
Charles Wade, Kylie Montgomery, Gabriela E. Jones, Peter Sellars, Akram A. Hosseini, Simon Paine, Henry Houlden, Mina Ryten, David S. Lynch   +8 more
wiley   +1 more source

The Impact and Reliability of Tissue Segmentation on In Vivo Magnetic Resonance Spectroscopy Metabolite Quantification

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Quantification of metabolite concentrations using MRS requires tissue‐dependent signal corrections. Accurate estimation of voxel tissue composition is therefore essential. Commonly used brain tissue segmentation tools differ in their algorithms and implementation, potentially introducing variability in MRS‐derived concentration ...
Jessica Archibald, Kay Chioma Igwe, Antonia Kaiser, Karl Landheer, Jaimie Lee, John L. K. Kramer, Aaron T. Gudmundson, Helge J. Zöllner, Georg Oeltzschner, Candace C. Fleischer, Niklaus Zölch, Jamie Near, Mark Mikkelsen   +12 more
wiley   +1 more source

Estimation of Intra and Inter-Individual Variability of Post Mortem Skin Hydration by Corneometry

Arab Journal of Forensic Sciences & Forensic Medicine
Kinetics of post mortem skin desiccation, potentially useful for post mortem interval (PMI) determination, is poorly understood. We therefore propose a preliminary study to assess intra- and inter-individual variability of post mortem skin hydration ...
Aurélien Partoune, Anne-Françoise Donneau, Nadia Dardenne, Philippe Boxho   +3 more
doaj   +1 more source

Hygrothermal Aging and Decoupled Axial‐Radial Compressive Failure Mechanisms in Glass Fiber Reinforced Epoxy Filament‐Wound Composite Tubes

Polymer Composites, EarlyView.
Composite cylinder under axial and radial compression. ABSTRACT This study examines the hygrothermal degradation of filament‐wound glass fiber‐reinforced epoxy composite tubes designed for application as liners in oil and gas systems, focusing on their response under axial or radial compression.
Anderson L. dos Santos, Maikson L. P. Tonatto, José Humberto S. Almeida Jr, Sandro C. Amico   +3 more
wiley   +1 more source

Dental DNA as an Indicator of Post-Mortem Interval (PMI): A Pilot Research. [PDF]

Int J Mol Sci, 2022
Bianchi I, Grassi S, Castiglione F, Bartoli C, De Saint Pierre B, Focardi M, Oliva A, Pinchi V.   +7 more
europepmc   +1 more source

Preclinical Efficacy and Safety Evaluation of a Novel Controlled‐Expansion ePTFE‐Covered TIPS Stent in a Swine Model

Portal Hypertension &Cirrhosis, EarlyView.
This preclinical study evaluated a novel controlled‐expansion expanded polytetrafluoroethylene (ePTFE)‐covered transjugular intrahepatic portosystemic shunt (TIPS) stent in 11 swine, demonstrating 100% technical success, excellent deployability, and durable 6‐month angiographic patency without thrombosis, migration, fracture, or device‐related toxicity.
Yi Xiang, Qi Zhang, Chuan Liu, Jiawei Zhang, Qingqiao Zhang, Changsheng Shi, Chunze Zhou, Yudong Zhang, Hongliang He, Hao Xie, Hui Shi, Haijian Guo, Wenjing Liu, Muqing Lin, Huajie Yu, Xiaolong Qi   +15 more
wiley   +1 more source

Leaf penetration by endophytic Metarhizium brunneum enables infection of Phthorimaea absoluta in tomato mines while inducing the crop defense system

Pest Management Science, EarlyView.
Spraying Metarhizium brunneum on tomato plants controls heterogeneous and upcoming Phthorimaea absoluta populations by infecting larvae within mines and priming plant induced systemic defences. Abstract BACKGROUND The endophytic entomopathogenic fungus Metarhizium brunneum Petch EAMa 01/58‐Su shows strong potential for managing Phthorimaea absoluta, a ...
Esther Aguilera Cuenca, María José García del Rosal, Fabián García Espinoza, Enrique Quesada Moraga, Irene Magdalena Rodríguez Gómez, Meelad Yousef Yousef   +5 more
wiley   +1 more source

Interpretation of post-mortem interval by analyzing the histological attributes of gingival mucosa — an observational study

Egyptian Journal of Forensic Sciences
Background Forensic odontology has been one of the most rapidly advancing fields within forensic science for decades. It goes beyond simply determining age and gender, playing a crucial role in estimating the post-mortem interval (PMI), which remains a ...
Ananya, Lipsa Bhuyan, Vidya G. Doddawad, Aishwariya Mohanty, Kanika Singh Dhull, Asutosh Das   +5 more
doaj   +1 more source

A small RNA, microRNA as a potential biomolecular marker to estimate post mortem interval in forensic science: a systematic review. [PDF]

Int J Legal Med, 2023
Pasaribu RS, Auerkari EI, Suhartono AW, Auerkari P.   +3 more
europepmc   +1 more source

Precise 3D Tracking of Highly Non‐Planar Eukaryotic Flagellar Beating Patterns Using Digital Holographic Microscopy

Small Methods, EarlyView.
The 3D beating dynamics of eukaryotic flagella drive motility, sensory functions, and resource acquisition, yet highly non‐planar beating patterns remain poorly characterized. Based on Digital Holographic Microscopy, holoV3C enables label‐free 3D reconstruction of such complex dynamics with 53 nm axial resolution, demonstrated on mouse sperm and ...
Patryk Nienaltowski, Jonasz Słomka, Federica Miano, Thomas Kiørboe, Clara Martínez‐Pérez, Tristan Colomb, Yves Emery, Roman Stocker   +7 more
wiley   +1 more source