Results 211 to 220 of about 88,248 (294)

DNA extracted from boiled archival fish bones yields high‐quality whole‐genome sequencing data

open access: yesJournal of Fish Biology, EarlyView.
Abstract Archival samples provide a unique source of organismal DNA, offering the potential to extend the temporal scale of genetic studies by decades to centuries. Fish hard structures, such as otoliths and scales, serve as records for fish collected during fisheries monitoring across a large spatiotemporal scale.
Jingyao Niu   +5 more
wiley   +1 more source

Newly identified intervertebral fat pad degenerates after intervertebral disc injury in a rat model of degeneration

open access: yesJournal of Anatomy, EarlyView.
This study characterizes a newly‐described intervertebral fat pad (IVFP) anterior to rat IVDs, with evidence for its existence in mice and human IVDs as well. In rats, the IVFP gradually degenerated following IVD injury with changes in adipocyte size and fibrous tissue infiltration, suggesting it could play a functional role in IVD health and ...
Niklas H. Koehne   +7 more
wiley   +1 more source

Neural modulation of ocular immunity: Exploring a sympathetic‐macrophage neuroimmune link in the human ciliary body

open access: yesJournal of Anatomy, EarlyView.
Using microscopy and 3D confocal imaging on seven cadaveric eyes, we identified sympathetic nerves closely associated with β₂‐adrenergic receptor‐expressing macrophages in the human ciliary body (CB). These findings suggest a sympathetic‐macrophage neuroimmune link in the CB, potentially influencing ocular inflammation and degeneration, warranting ...
Tanya S. Karakyriakou   +6 more
wiley   +1 more source

A Possible New Approach for Determining the Post-Mortem Interval

open access: yesThe Journal of Criminal Law, Criminology, and Police Science, 1971
Lorenzen, Gerald A., Lawson, Rommon L.
openaire   +2 more sources

The therapeutic role of exercise training during menopause for reducing vascular disease

open access: yesExperimental Physiology, EarlyView.
Abstract Menopause marks a major milestone in female reproductive ageing. It is characterized by the cessation of ovarian function and a concomitant decline in hormones such as oestradiol. Subsequently, females undergoing menopausal transition experience a progressive increase in cardiovascular and cerebrovascular disease risk.
Conan L. H. Shing   +4 more
wiley   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand   +2 more
wiley   +1 more source

Mechanical sensitization of sensory afferents after passive transfer of fibromyalgia IgG

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In addition to widespread pain and fatigue, people with fibromyalgia (FM) experience sensory abnormalities and report lingering, painful sensations after touch or mechanical probing of the skin. Administration of IgG purified from FM patients to mice transfers symptoms and signs of FM.
Mathilde R. Israel   +5 more
wiley   +1 more source

Developing a Natural Language Processing Strategy to Avoid Biased Data in Electronic Health Record Suicide Risk Modeling

open access: yesPsychiatric Research and Clinical Practice, EarlyView.
Objective Unstructured electronic health record (EHR) data is increasingly used to enhance suicide risk modeling. Unfortunately, EHR reported death dates are frequently inaccurate. Including EHR data from after patients' deaths, or after suicidal actions which led to their deaths, potentially biases suicide prediction models.
Maxwell Levis   +3 more
wiley   +1 more source

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