Results 91 to 100 of about 538 (216)
Advanced Science, EarlyView.ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang +11 more
wiley +1 more source
The Costs and Benefits of Mindfulness and Reappraisal in Daily Life Postdoc Postdoc Postdoc
Reappraisal and mindfulness represent two fundamentally different ways of dealing with one’s emotions: Whereas reappraisal aims at changing one’s thoughts and emotions, mindfulness is aimed at not changing, but appreciating them. Despite this difference, prior research has shown that both are similarly associated with short-term benefits and trait ...
Mario Wenzel +3 more
openaire +1 more source
Advanced Science, EarlyView.ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo +14 more
wiley +1 more source
Effects of Participation in Domestics Mobility for Young Researchers and Lecturers
Вопросы образованияIn the context of a significant reduction in international mobility for Russian scientists, the importance of domestic programs is increasing. This study aims to assess the scale of domestic academic mobility programs, create a profile of those ...
Alena I. Nefedova +3 more
doaj +1 more source
Physical Origin of Temperature Induced Activation Energy Switching in Electrically Conductive Cement
Advanced Science, EarlyView.The temperature‐induced Arrhenius activation energy switching phenomenon of electrical conduction in electrically conductive cement originates from structural degradation within the biphasic ionic‐electronic conduction architecture and shows percolation‐governed characteristics: pore network opening dominates the low‐percolation regime with downward ...
Jiacheng Zhang +7 more
wiley +1 more source
Advanced Science, EarlyView.AUTACE is a bifunctional nanoplatform that integrates tumor targeting, immune engagement, and on‐demand KRAS degradation. It targets KRAS/TP53 co‐mutant tumors via TP53‐specific TCRs, elicits antitumor CD8+ T‐cell responses through surface anti‐CD3 antibodies, and uses low‐intensity focused ultrasound (LIFU) to trigger controlled release of the KRAS ...
Luo Li +6 more
wiley +1 more source
CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation
Advanced Science, EarlyView.ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu +10 more
wiley +1 more source
Sådan kan evaluering styrke læring, samarbejde og forbedring i komplekse offentlige velfærdsarenaer!
Cepra-StribenArtiklen præsenterer en model for kollaborativ evaluering (også kaldet samarbejdsevaluering), der ligger i forlængelse af den mere involverende evalueringstrend Den femte evalueringsbølge.
Charlotte Laubek
doaj +1 more source
Advanced Science, EarlyView.Soybean employs its circadian clock, governed by GmCCA1, to rhythmically defend against soybean cyst nematodes. The pathogen retaliates by secreting the effector Hg4E02, which hijacks the clock to suppress defense and co‐opt the host's translation machinery for nutrient acquisition.
Xingwei Wang +21 more
wiley +1 more source