Results 21 to 30 of about 15,297 (265)
How postdocs benefit from building a union
eLife, 2014 Members of UAW 5810—the union for postdoctoral researchers at the University of California—describe how their union has led to improved terms and conditions for postdocs.
Benjamin Cain +4 more
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A fair deal for PhD students and postdocs
eLife, 2013 The relentless expansion that threatens the sustainability of biomedical research in the US takes a heavy toll on young researchers.
Henry R Bourne
doaj +1 more source
Learning from the Ethics of AI – A Research Proposal on Soft Law and Ethics of AI
Tilburg Law Review, 2023 This contribution outlines a research proposal combining ethical guidelines on AI and a law-as-data approach. Building upon the definitions of soft law discussed in legal scholarship, it proposes a way of structuring the regulatory landscape on AI and of
Johan Rochel
doaj +1 more source
The changing career paths of PhDs and postdocs trained at EMBL
eLife, 2023 Individuals with PhDs and postdoctoral experience in the life sciences can pursue a variety of career paths. Many PhD students and postdocs aspire to a permanent research position at a university or research institute, but competition for such positions ...
Junyan Lu +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Nordisk Kulturpolitisk Tidsskrift, 2022 Based on nationally representative survey data from a large European project on the societal values of culture, this article measures Danes’ and Finns’ cultural participation in a broad range of activities before COVID-19 disrupted the globe, and what ...
Eva Myrczik +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
eLife, 2013 Eve Marder explains why all scientists should spend time living and working in a foreign country.
Eve Marder
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Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source