Results 21 to 30 of about 538 (216)

Learning from the Ethics of AI – A Research Proposal on Soft Law and Ethics of AI

Tilburg Law Review, 2023
This contribution outlines a research proposal combining ethical guidelines on AI and a law-as-data approach. Building upon the definitions of soft law discussed in legal scholarship, it proposes a way of structuring the regulatory landscape on AI and of
Johan Rochel
doaj   +1 more source

Luck, jobs and learning

eLife, 2013
Eve Marder believes that many of the most important events in our lives, both personal and professional, depend to some degree on luck or chance.
Eve Marder
doaj   +1 more source

The changing career paths of PhDs and postdocs trained at EMBL

eLife, 2023
Individuals with PhDs and postdoctoral experience in the life sciences can pursue a variety of career paths. Many PhD students and postdocs aspire to a permanent research position at a university or research institute, but competition for such positions ...
Junyan Lu, Britta Velten, Bernd Klaus, Mauricio Ramm, Wolfgang Huber, Rachel Coulthard-Graf   +5 more
doaj   +1 more source

A recipe for mediocrity and disaster, in five axioms

eLife, 2013
Biomedical research in the US will become unsustainable unless scientists and research institutions start to question certain assumptions they have long taken for granted.
Henry R Bourne
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

How postdocs benefit from building a union

eLife, 2014
Members of UAW 5810—the union for postdoctoral researchers at the University of California—describe how their union has led to improved terms and conditions for postdocs.
Benjamin Cain, Jessica M Budke, Kelsey J Wood, Neal T Sweeney, Benjamin Schwessinger   +4 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

“Missing out on culture—or not: Danes and Finns’ cultural participation, the pandemic, and cultural policy measures”

Nordisk Kulturpolitisk Tidsskrift, 2022
Based on nationally representative survey data from a large European project on the societal values of culture, this article measures Danes’ and Finns’ cultural participation in a broad range of activities before COVID-19 disrupted the globe, and what ...
Eva Myrczik, Riie Heikkilä, Nete Nørgaard Kristensen, Semi Purhonen   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

A fair deal for PhD students and postdocs

eLife, 2013
The relentless expansion that threatens the sustainability of biomedical research in the US takes a heavy toll on young researchers.
Henry R Bourne
doaj   +1 more source