Results 211 to 220 of about 1,455,570 (291)

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Health Care Managers' Role and Challenges in Implementing Hepatitis B Vaccination for Health Care Workers in a Tertiary Setting. [PDF]

Indian J Community Med
Bali S, Gouroumourty R.
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Correspondence on "Mass Balance Tracing of In Vivo Biodistribution, Relocation, and Excretion of Europium-Doped Micro/Nanoplastics in Rats". [PDF]

Environ Sci Technol
Gañán-Calvo AM.
europepmc   +1 more source

Figuring Post-worker Shenzhen

Made in China Journal, 2018
openaire   +2 more sources

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

Evaluating the effectiveness and utilization of the primary emergency care training in Nepal: a longitudinal mixed methods study. [PDF]

BMC Emerg Med
Bhandari R, Kalaunee ABC, Amatya A, Ghimire YC, Lamsal MP, Chitrakar D, Bhusal BR, Thapa A, Knoble A, Paudel P, Rajbhandari R.   +10 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Evaluation of the measles surveillance system in Chereponi District, Ghana, 2019-2024. [PDF]

Public Health Pract (Oxf)
Dzeha R, Amponsah O.
europepmc   +1 more source

Access to Information on the Posting of Workers

Elif Naz Kayran, Eszter Zólyomi, Lynn De Smedt, Frederic De Wispelaere, Rossana Cillo, Fabio Perocco, Alexandra Moran, Lucia Mýtna Kureková   +7 more
openaire   +1 more source