Results 1 to 10 of about 4,681 (199)

Gremlin is a potential target for posterior capsular opacification [PDF]

open access: yesCell Cycle, 2019
Objective: The present study was conducted to determine the role of gremlin during the development of posterior capsular opacification (PCO) via in vitro and in vivo experiments. Methods: The activation, roles and relationships of the BMPs/Smad1/5, MAPK, FAK and AKT signaling pathways in human lens epithelial cells (HLECs) after gremlin induction were ...
Ruihua Jing, Tiantian Qi
exaly   +6 more sources

Preserving posterior capsular integrity in post-endothelial keratoplasty posterior capsular opacification [PDF]

open access: yesIndian Journal of Ophthalmology, 2021
Endothelial keratoplasty (EK) with pseudophakia often presents with late-onset proliferative after-cataract with posterior capsule distension. We performed a modified technique of capsular bag lavage in 11 eyes with late-onset PCO after EK (4 cases: post-
Jeewan Singh Titiyal   +3 more
doaj   +4 more sources

αVβ8 integrin targeting to prevent posterior capsular opacification [PDF]

open access: yesJCI Insight, 2021
Fibrotic posterior capsular opacification (PCO), a major complication of cataract surgery, is driven by transforming growth factor–β (TGF-β). Previously, αV integrins were found to be critical for the onset of TGF-β–mediated PCO in vivo; however, the ...
Mahbubul H. Shihan   +8 more
doaj   +6 more sources

“NIR-triggered ROS storage” photodynamic intraocular implant for high-efficient and safe posterior capsular opacification prevention [PDF]

open access: yesAsian Journal of Pharmaceutical Sciences, 2022
Posterior capsular opacification (PCO) is the leading cause of vision loss after cataract, mainly caused by the adhesion, proliferation and trans-differentiation of post-operative residual lens epithelial cells (LECs).
Yanjuan Huang   +7 more
doaj   +3 more sources

INCIDENCE OF POSTERIOR CAPSULAR OPACIFICATION AFTER UNEVENTFUL CATARACT SURGERY IN PATIENTS ON HEMODIALYSIS

open access: yesSanamed, 2019
Purpose: To evaluate the incidence of posterior capsular opacification after cataract surgery in patients on hemodialysis. Patients and Methods: Fifty patients on hemodialysis undergoing cataract surgery and 50 patients undergoing cataract surgery in a ...
Yildiz Aydin, Comez Taskiran Arzu
doaj   +3 more sources

Posterior capsular opacification: A review

open access: yesIndian Journal of Ophthalmology, 2013
Posterior capsular opacification (PCO) is the most frequent complication of cataract surgery. Advances in surgical techniques, intraocular lens (IOL) materials, and designs have reduced the PCO rate; however, it remains a significant problem resulting in suboptimal outcome of cataract surgery.
Rajesh Sinha   +4 more
doaj   +2 more sources

Prevention of posterior capsular opacification

open access: yesExperimental Eye Research, 2015
Posterior capsular opacification (PCO) is a common complication of cataract surgery. The development of PCO is due to a combination of the processes of proliferation, migration, and transdifferentiation of residual lens epithelial cells (LECs) on the lens capsule.
Lisanne M. Nibourg   +5 more
core   +5 more sources

An Optical Section-Assisted In Vivo Rabbit Model for Capsular Bend and Posterior Capsule Opacification Investigation. [PDF]

open access: yesPLoS ONE, 2016
To establish an optical section-assisted in vivo rabbit model for capsular bend and posterior capsule opacification (PCO) investigation.A total of 10 rabbits underwent phacoemulsification surgery and intraocular lens (IOL) implantation.
Pingjun Chang   +9 more
doaj   +2 more sources

Three-year study in patients with posterior capsular opacification [PDF]

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2017
Background: posterior capsular opacification is still the most frequent late postoperative complication after cataract surgery.Objective: to describe the results of the study of patients with posterior capsular opacification, attended to at “Guillermo ...
Juan Carlos Góngora Torres   +4 more
doaj   +1 more source

Posterior Capsular Opacification in Preschool- and School-Age Patients after Pediatric Cataract Surgery without Posterior Capsulotomy

open access: yesTürk Oftalmoloji Dergisi, 2016
Objectives: We aimed to evaluate the development of posterior capsular opacification (PCO) in preschool- and school-age children with cataract who underwent cataract surgery without posterior capsulotomy and anterior vitrectomy.
Muhammed Batur   +4 more
doaj   +2 more sources

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