Results 121 to 130 of about 1,781,168 (298)

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Verknöcherungsraten von Posterior Lumbar Interbody Fusion (PLIF) ohne Knochentransplantat bei degenerativ bedingter Instabilität der lumbalen Wirbelsäule

open access: yes
VERKNÖCHERUNGSRATEN VON POSTERIOR LUMBAR INTERBODY FUSION (PLIF) OHNE KNOCHENTRANSPLANTAT BEI DEGENERATIV BEDINGTER INSTABILITÄT DER LUMBALEN WIRBELSÄULE Verknöcherungsraten von Posterior Lumbar Interbody Fusion (PLIF) ohne Knochentransplantat bei ...
Buchholz, Kaye Marie
core  

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Cage and cross-sectional view of the posterior lumbar interbody fusion model.

open access: yes, 2016
(A) Lateral view of the polyetheretherketone (PEEK) cage, and (B) cross-sectional view of the posterior lumbar interbody fusion model with one diagonally placed PEEK cage.
Jian-Hua Lin (409397)   +9 more
core   +1 more source

The evolution of posterior cervical fusion: A tribute to Frederick P. Dewar, M.D. and Edward. H. Simmons, M.D.

open access: yesWorld Neurosurgery: X
This historical vignette is a tribute to Professors Frederick P. Dewar and Edward H. Simmons who were pioneers in the evolution of posterior cervical fusion.
Morgan P. Lorio   +4 more
doaj   +1 more source

Early outcomes in hybrid fixation for idiopathic scoliosis: posterior fusion combined with anterior vertebral body tethering. Patient series. [PDF]

open access: yesJ Neurosurg Case Lessons, 2023
Cherian D   +7 more
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Clinical and radiographic benefits of skipping C7 instrumentation in posterior cervicothoracic fusion: a retrospective analysis.

open access: yes, 2022
BACKGROUND: C7 instrumentation during posterior cervicothoracic fusion can be challenging because it requires additional work of either placing side connectors to a single rod or placing two rods.
Patel, Saavan   +5 more
core  

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