Results 161 to 170 of about 10,323 (277)

DOTA‐grafted Cationic Polymers Behaving as Powerful Macromolecular Resistance‐reversal Agents (MRRAs) Combating Against New Delhi Metallo‐β‐lactamase (NDM)‐producing Bacteria

Advanced Science, EarlyView.
Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang, Jian Zhang, Yun li, Liping Qiao, Zhuorui Dong, Dandan Cui, Peirong Bai, Liping Li, Bing Cao, Ruiping Zhang   +9 more
wiley   +1 more source

Outpatient visits and secondary surgeries following open globe injuries: a single institution retrospective analysis. [PDF]

Int Ophthalmol
Vought R, Vought V, Henry RK, Oydanich M, Khouri AS.   +4 more
europepmc   +1 more source

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source

Hunting Firearm Induced Optic Nerve Transection. [PDF]

Int Med Case Rep J
Calabresi V, Cuccu A, Corda C, Giannaccare G.   +3 more
europepmc   +1 more source

Exacerbation of blast-induced ocular trauma by an immune response [PDF]

, 2014

core   +1 more source

Endothelial GPR68 Is Essential for Arteriogenesis and Represents a Therapeutic Target in a Model of Peripheral Artery Disease

Advanced Science, EarlyView.
Endothelial GPR68 is identified as a critical regulator of collateral artery growth in peripheral artery disease. Genetic and pharmacological evidence demonstrates that GPR68 integrates hemodynamic cues to drive monocyte recruitment and inflammatory remodeling, thereby promoting collateral arteriogenesis and tissue perfusion after ischemia ...
Yiyan Song, Senyi Peng, Zhilei Huang, Miao Yu, Mingyue Wu, Yuexin Zhu, Zeyi Zhou, Yongshan Liu, Yalin Zhang, Yu Huang, Zhongxing Wang, Fu‐Li Xiang, Jie Xu   +12 more
wiley   +1 more source

Ocular injuries following the pager explosion mass casualty event in Lebanon: a large single-centre case series. [PDF]

Br J Ophthalmol
Saade J, Kheir WJ, Hassoun M, Al Hassan S, Bou Ghannam A, Noureddine B, Bashshur Z, Awwad ST, Hamam RN, Mansour AM, Haddad R, Massoud V, Gendy JE, Khalil A, Ibrahim H, Tabaja J, Bteich Y, Ismail A, M Alameddine R.   +18 more
europepmc   +1 more source

Controversies and Advances of Orbital Fractures and Reconstruction [PDF]

, 2013
Leung, MYY
core  

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

<i>Clostridium perfringens</i> infection following open globe injury due to firecracker blast: A rare case report from Southern India. [PDF]

IDCases
Jayagandan S, Stephen M, Bagavane S, Biswas R, Deb AK.   +4 more
europepmc   +1 more source