Results 51 to 60 of about 9,639 (200)

Posterior reversible encephalopathy syndrome (PRES)

BMJ Case Reports, 2009
Urgent haemodialysis was started in a 66-year-old woman with uraemic drowsiness and a history of chronic kidney disease (CKD) (stage 5, blood urea nitrogen (BUN) 141.3 mg/dl, creatinine 14.8 mg/dl) with poorly controlled hypertension (baseline level 190/75 mm Hg). Her consciousness cleared 3 days later.
Chin-Chi, Kuo, Chun-Chieh, Huang, Jeng-Wen, Huang, Aristine, Cheng, Ching-Wei, Tsai, Ming-Shiou, Wu   +5 more
openaire   +3 more sources

An n‐of‐1 gene‐directed drug repurposing trial for an ultrarare genetic condition

Epilepsia, EarlyView.
Abstract Objective Gain‐of‐function (GoF) variants in the KCNC1 potassium channel subunit gene (Kv3.1) cause motor/cognitive delays and hypotonia and have been associated with seizures. Fluoxetine has inhibitory effects on Kv3.1. However, open‐label nonrandomized administration is insufficient to guide clinical decision‐making in ultrarare conditions ...
Vedika Jha, Christina Tsetsos, Mark Bedford, Gregory Costain, Sunita Vohra, Juan Pablo Diaz Martinez, Elise Heon, Jacob Vorstman, Carolina Gorodetsky, Ajoy Vincent, Jesiqua Rapley, Lori Anderson, Evdokia Anagnostou, Danielle A. Baribeau   +13 more
wiley   +1 more source

Pressurized Contrast‐Related Posterior Reversible Encephalopathy Syndrome After Cerebral Digital Subtraction Angiography

Stroke: Vascular and Interventional Neurology
Posterior reversible encephalopathy syndrome is a multifactorial neurological disorder characterized by clinical and neuroimaging findings. The “vasogenic theory” suggests that, in this condition, disrupted cerebrovascular autoregulation leads to blood ...
Lea Scherschinski, Tyler D. Schriber, Stefan W. Koester, Adam T. Eberle, Joshua S. Catapano, Ethan A. Winkler, Felipe C. Albuquerque, Michael T. Lawton, Andrew F. Ducruet, Ruchira M. Jha, Ashutosh P. Jadhav   +10 more
doaj   +1 more source

Gemcitabine Monotherapy Associated with Posterior Reversible Encephalopathy Syndrome

Case Reports in Oncology, 2011
Posterior reversible encephalopathy syndrome is a clinicoradiologic entity that may present with headaches, altered mental status, seizures and visual loss as well as specific neuroimaging findings.
Luiz Carlos Porcello Marrone, Bianca Fontana Marrone, Julia de la Puerta Raya, Giovani Gadonski, Jaderson Costa da Costa   +4 more
doaj   +1 more source

Acute Intermittent Porphyria, Posterior Reversible Encephalopathy Syndrome and Hypertensive Emergency, A Review of The Literature

Egyptian Journal of Critical Care Medicine, 2020
Acute intermittent porphyria is an autosomal dominant inborn error characterized by decreased activity of porphobilinogen deaminase leading to increased levels of haem precursors, namely aminolevulinic acid and porphobilinogen.
Mohamed A. Ahmed, Mahmoud Abdelnabi, Abdallah Almaghraby   +2 more
doaj   +1 more source

Compound heterozygous SLC12A5 variants expand the molecular and functional spectrum of KCC2‐developmental and epileptic encephalopathy

Epilepsia, EarlyView.
Overview of the multimodal experimental approach integrating clinical, genetic, in silico, and in vitro investigations. Clinical: Representative EEG recording setup and ictal traces from affected patients. Genetic: Pedigrees for Families A and B highlighting the inheritance of the four identified SLC12A5 variants (A1, A2, B1, B2).
Mira Hamze, Robyn Whitney, Dorothée Ville, Nathalie Villeneuve, Anna‐Maria Hartmann, Lisa Becker, Jens Hausmann, Jinwei Zhang, Cathy Brier, Lucie I. Pisella, Perrine Friedel, Audrey Labalme, Eudeline Alix, Nicolas Chatron, Damien Sanlaville, Sylvie Gory‐Fauré, Eric Denarier, Christophe Porcher, Gaetan Lesca, Igor Medina   +19 more
wiley   +1 more source

Posterior reversible encephalopathy syndrome secondary to asymptomatic poststreptococcal glomerulonephritis in a child with sickle cell anemia: a case report

Journal of Medical Case Reports, 2018
Background Posterior reversible encephalopathy syndrome is a neurotoxic condition that occurs as a result of the failure of posterior circulatory autoregulation in response to acute changes in blood pressure.
Ehab Hanafy, Duaa Alshareef, Suhaila Osman, Abdullah Al Jabri, Faisal Nazim, Gihan Mahmoud   +5 more
doaj   +1 more source

Malignant Posterior Reversible Encephalopathy Syndrome: A Case of Posterior Irreversible Encephalopathy Syndrome [PDF]

Journal of Clinical Neurology, 2016
Dear Editor, Posterior reversible encephalopathy syndrome (PRES) is a clinicoradiologic syndrome characterized by predominant parietal and occipital lobe edema that is mainly reversible within a few days.1,2 However, many atypical patterns have been identified.3 Reversibility is not always achieved,3 which exposes a contradiction in this supposedly ...
Martins, William Alves, Marrone, Luiz Carlos Porcello   +1 more
openaire   +2 more sources

Effects of fenfluramine and sigma‐1‐dependent pharmacological and genetic modulation in a mouse kindling model

Epilepsia, EarlyView.
Abstract Objective Sigma‐1 is a chaperone protein that serves as a key homeostatic regulator, implicated in neuronal excitability and seizure control. Positive allosteric modulators offer a use‐dependent means to enhance Sigma‐1 activity, potentially with favorable tolerability compared to direct agonists.
Eva‐Lotta von Rüden, Verena Buchecker, Amelie Wagner, Victoria M. Stocker, Liga Zvejniece, Heidrun Potschka   +5 more
wiley   +1 more source

Near fatal posterior reversible encephalopathy syndrome complicating chronic liver failure and treated by induced hypothermia and dialysis: a case report

Journal of Medical Case Reports, 2009
Introduction Posterior reversible encephalopathy syndrome is a clinico-neuroradiological entity characterized by headache, vomiting, altered mental status, blurred vision and seizures with neuroimaging studies demonstrating white-gray matter edema ...
Chawla Rashmi, Smith Daniel, Marik Paul E   +2 more
doaj   +1 more source