Results 81 to 90 of about 46,748 (269)
Advanced Science, EarlyView.AAV2.7m8 serotype combined with the gfaABC1D promoter targets infection of supporting cells (SCs). AAV2.7m8‐gfaABC1D‐Gjb2 administration to mice results in excessive immune responses. The combination of AAV2.7m8‐gfaABC1D‐Gjb2 with dexamethasone (DEX) shows a synergistic effect and enhances the gene therapy effect in a conditional Cx26 null mice model ...
Xiaohui Wang +8 more
wiley +1 more source
International Archives of Otorhinolaryngology, 2021 Introduction Benign Paroxysmal Positional Vertigo (BPPV) is the most common vestibular disorder, resulting from detached otoliths that migrate to one of the semicircular canals – canalolithiasis – or one of the cupulas – cupulolithiasis.
Bernardo Faria Ramos +4 more
doaj +1 more source
Advanced Science, EarlyView.Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu +7 more
wiley +1 more source
HSV-1 not only in human vestibular ganglia but also in the vestibular labyrinth [PDF]
, 2001 Reactivation of herpes simplex virus type 1 (HSV-1) in the vestibular ganglion (VG) is the suspected cause of vestibular neuritis (VN). Recent studies reported the presence of HSV-1 DNA not only in human VGs but also in vestibular nuclei, a finding that ...
Arbusow, Viktor +4 more
core +1 more source
Frontiers in Neurology, 2021 Objective: In the present study, we characterized the vestibulo-ocular reflex (VOR) gain and properties of corrective saccades (CS) in patients with posterior inferior cerebellar artery (PICA) stroke and determined the best parameter to differentiate ...
Gi-Sung Nam +8 more
doaj +1 more source
Posterior semicircular canal dehiscence following endolymphatic sac surgery [PDF]
The Laryngoscope, 2012 AbstractPosterior semicircular canal dehiscence is a rare otologic entity that presents with third window signs and symptoms. Petrous apex cholesteatoma, fibrous dysplasia, high riding jugular bulb, and eosinophilic granuloma have been reported to be associated with posterior semicircular canal dehiscence.
Hossein Mahboubi +2 more
openaire +3 more sources
AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells
Advanced Science, EarlyView.Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu +8 more
wiley +1 more source
Atypical Bilateral Posterior Semicircular Canalolithiasis – A Case Series
Annals of Indian Academy of NeurologyBarany Society includes bilateral typical posterior semicircular canal benign paroxysmal positional vertigo (PSC-BPPV) in its classification of multicanal subtype.
Ajay K Vats +3 more
doaj +1 more source
Revista de la Facultad de Medicina, 2017 Introducción. El Vértigo Posicional Paroxístico Benigno (VPPB) del canal semicircular posterior es una enfermedad crónica que afecta severamente la calidad de vida de los pacientes que lo sufren. Para su manejo existen las Maniobras de Reposicionamiento,
Mario Loarca +3 more
doaj +1 more source
Semicircular canals in Anolis lizards: ecomorphological convergence and ecomorph affinities of fossil species [PDF]
Royal Society Open Science, 2017 Anolis lizards are a model system for the study of adaptive radiation and convergent evolution. Greater Antillean anoles have repeatedly evolved six similar forms or ecomorphs: crown-giant, grass-bush, twig, trunk, trunk-crown and trunk-ground.
Blake V. Dickson +3 more
doaj +1 more source