Results 241 to 250 of about 14,932 (301)

A morphometric study of posterior tibial slope differences by sex and ethnicity in a South African population. [PDF]

Surg Radiol Anat
Hohmann E, Nel A, Zyl RV, Keough N, Mogale N.   +4 more
europepmc   +1 more source

Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Single‐cell RNA sequencing (scRNA‐seq) maps how distinct driver mutations remodel hematopoietic stem cell (HSC) programs across essential thrombocythemia (ET). Comparative analysis uncovers both shared and subtype‐specific molecular signatures, identifies a triple‐negative (TN)‐associated HSC population enriched with malignant traits, and reveals the ...
Jingyuan Tong, Di Wang, Haoze Song, Ting Sun, Yanhong Zhao, Wenjing Gu, Lexuan Lin, Yitong Zhao, Yipeng Liang, Xu Jin, Rongfeng Fu, Mankai Ju, Jie Gao, Jinfa Ma, Chengjie Gao, Anqi Zhang, Zhijian Xiao, Erlie Jiang, Renchi Yang, Shihui Ma, Lei Zhang, Lihong Shi   +21 more
wiley   +1 more source

PRISM‐xQTL: Pleiotropic Relationships Integrated with System‐level Multiomic QTL analysis for causal genes and molecular mediators in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Most Alzheimer's disease (AD) risk variants identified by genome‐wide association studies (GWAS) reside in noncoding regions, complicating causal interpretation. METHODS We developed PRISM‐xQTL (Pleiotropic Relationships Integrated with System‐level Multiomic QTL), integrating pleiotropy, co‐localization, Mendelian randomization ...
Nitesh Enduru, Zhongming Zhao
wiley   +1 more source

Plate-Controlled Correction of Sagittal Plane Knee Deformities: The Entire-Segment Rotation Technique for Correcting Varus and Posterior Tibial Slope. [PDF]

Arthrosc Tech
Aldawoudy A, Abohatab M, Aboutawila MA, Elagwany M, Gawish HM.   +4 more
europepmc   +1 more source

UBL3 Participates in the Early Stages of CD83‐Dependent CD4+ T Cell Selection

European Journal of Immunology, Volume 56, Issue 2, February 2026.
CD83 and UBL3 are regulators of MHCII surface expression; however, only CD83 has a known role in regulating CD4+ T cell selection. This paper describes a role for UBL3 in regulating MHC II expression on thymic epithelium in a CD83‐deficient context, leading to alterations in CD4+ T cell positive selection.
Huw Morgan, Haiyin Liu, Jose A. Villadangos, Justine D. Mintern   +3 more
wiley   +1 more source

Multi‐Omics Revealed the Effects of Intrauterine Hyperglycemia Exposure on the Development of Skeletal Muscle in Offspring

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Gestational diabetes mellitus (GDM), a common pregnancy complication characterized by maternal hyperglycemia, negatively impacts offspring health. Skeletal muscle, a critical tissue for glucose and lipid metabolism, is especially vulnerable to prenatal environmental insults.
Rui Liu, Junsen She, Xinyuan Li, Yishang Yan, Jiaying Mo, Jianzhong Sheng, Hongbo Yang, Hefeng Huang   +7 more
wiley   +1 more source

Slope-reducing tibial osteotomy combined with primary or revision ACL reconstruction improves knee stability and subjective function in patients with steep posterior tibial slope: a systematic review and meta-analysis. [PDF]

Int J Surg
Wang D, Di M, Zheng T, Zhang H.
europepmc   +1 more source

Targeted adjustment of the posterior tibial slope in unicompartmental knee arthroplasty is feasible without altering the medial proximal tibial angle. [PDF]

J Exp Orthop
El Kayali MKD, Berndt R, Gwinner C, Pichler L.   +3 more
europepmc   +1 more source

Automated Posterior Tibial Slope Measurement Using Lateral Knee Radiographs: A Novel Landmark-Based Approach Using Deep Learning. [PDF]

Orthop J Sports Med
Ryu B, Nam JW, Ro DH, Martin RK, Inderhaug E, Persson A, Haland S, Kim SE.   +7 more
europepmc   +1 more source

Evaluating the Mechanical Axis for Detection of Posterior Tibial Slope Malalignment in ACL-Deficient Knees on Lateral Radiographs. [PDF]

Orthop J Sports Med
Mayer P, Hielscher L, Schuster P, Schlumberger M, Rolvien T, Geßlein M, Beel W, Richter J.   +7 more
europepmc   +1 more source