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Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen +7 more
wiley +1 more source
Posterior Uveitis Secondary to Syphilis [PDF]
A 24-year-old man presented to the ophthalmologist complaining of decreased vision and intermittent dull pain in the left eye of 5-months duration. Ophthalmologic examination revealed visual acuity of 20/70, mild inflammatory reaction in the anterior chamber, vitreous haze (blur in figure 1 ▶), optic nerve edema, and retinal arteriolar narrowing and ...
Gaurav, Gupta, Dmitry, Pyatetsky
openaire +2 more sources
Voclosporin‐induced gingival enlargement: A case report
Abstract Background Drug‐influenced gingival enlargement (DIGE) is a recognized adverse effect of certain medications, particularly immunosuppressants like cyclosporin and tacrolimus. However, there have been no documented cases of DIGE associated with voclosporin, a newer calcineurin inhibitor used primarily to treat lupus nephritis.
Francesca Racca +2 more
wiley +1 more source
Clinical Manifestations and Treatment Outcomes of Syphilitic Uveitis in a Chinese Population
Purpose. To describe the clinical manifestations and treatment outcomes of syphilitic uveitis in a Chinese population. Methods. This is a retrospective case series of 15 consecutive patients with syphilitic uveitis treated at a uveitis referral center ...
Rui Zhang +6 more
doaj +1 more source
Introduction We investigated the frequency of uveitic macular edema (UME) in patients with different types of noninfectious uveitis and present the primary treatment methods for UME at a specialized eye center in Shaanxi Province, China.
Yan-Qi Xue, Jin-An Xiao, Ying Chen
doaj +1 more source
Retinal S-antigen Th1 cell epitope mapping in patients with Behcet's disease [PDF]
Background - Retinal S-antigen (S-Ag) is a most characterized autoantigen of autoimmune uveitis. The recognized immunodominant epitope of human S-Ag in patients with uveitis has not been identified. In this study, we selected certain patients with active
Du, L.P. +6 more
core +2 more sources
High prevalence of anelloviruses in vitreous fluid of children with seasonal hyperacute panuveitis. [PDF]
Seasonal hyperacute panuveitis (SHAPU) is a potentially blinding ocular disease occurring in Nepal that principally affects young children. Random amplification of partially purified vitreous fluid (VF)-derived nucleic acid revealed the presence of human
Baarsma, G Seerp +8 more
core +1 more source
Abstract Introduction Pre‐eclampsia (PE) involves systemic endothelial dysfunction and microvascular injury, yet routine obstetric care lacks noninvasive readouts of maternal microvascular health. We evaluated whether hypertensive retinopathy (HR) detected during pregnancy is associated with maternal disease severity and adverse neonatal outcomes ...
Gabriele Saccone +6 more
wiley +1 more source
Background This study aimed to assess and compare the clinical value of aqueous humor polymerase chain reaction (PCR) and serologic tests in patients diagnosed with suspected infectious uveitis.
Wungrak Choi +7 more
doaj +1 more source
Soluble Epoxide Hydrolase Inhibition for Ocular Diseases: Vision for the Future [PDF]
Ocular diseases cause visual impairment and blindness, imposing a devastating impact on quality of life and a substantial societal economic burden. Many such diseases lack universally effective pharmacotherapies.
Corson, Timothy W., Park, Bomina
core +1 more source

