Results 21 to 30 of about 812,761 (141)

Ocular Tuberculosis in Pediatrics: A Case Report

Acta Médica Portuguesa, 2023
A 17-year-old male was taken to the emergency department for decreased left visual acuity and floaters beginning that same day. There was a history of exposure to pulmonary tuberculosis five years before (mother as index case) followed by a four-month ...
Paula Manuel Vieira, Carla Zilhão, Vasco Miranda   +2 more
doaj   +1 more source

Posterior vitreous detachment in absentia.

, 2022
The relationship between the vitreous body, posterior vitreous detachment (PVD) and retina has been the focus of much research for over a hundred years [1-10 and references therein] and yet in spite of such prolonged investigation, there is still much ...

core   +2 more sources

INDUCTION OF POSTERIOR VITREOUS DETACHMENT IN PEDIATRIC PATIENTS BY RADIAL PERIFOVEAL STRIPPING

, 2022
BACKGROUND/PURPOSEIn certain cases, there may be firm adherence of the cortical vitreous to the retinal surface during pars plana vitrectomy. This report aims to present an alternative method of posterior vitreous detachment (PVD) induction at the macula
Audina M. Berrocal, Nimesh A. Patel, Patel, Nimesh A, Berrocal, Audina M   +3 more
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Correlation of inflammatory and proangiogenic cytokines from undiluted vitreous samples with spectral domain OCT scans, in untreated branch retinal vein occlusion [PDF]

, 2013
Purpose: To assess the levels of inflammatory and angiogenic cytokines in undiluted vitreous from treatment-naïve patients with macular edema secondary to nonischemic branch retinal vein occlusion (BRVO), with flow cytometric bead array (CBA) and to ...
Michaelis, Martin, Cinatl, Jindrich, Koch, Frank H., Schubert, Ralf, Koss, Michael J, Pfister, Marcel, Rothweiler, Florian, Koch, Frank H, Koss, Michael Janusz   +8 more
core   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

Risk factors for multiple retinal tears in patients with acute posterior vitreous detachment [PDF]

, 2018
WOS: 000428760800037PubMed ID: 28160191Purpose To evaluate possible risk factors for multiple retinal tears in patients with acute posterior vitreous detachment.
Aydin, Rukiye, Kaynak, Süleyman, Karti, ÖMER, Çam, Duygu, Zengin, Mehmet Özgür, Kartı, Ömer, Aydın, Rukiye, Karahan, Eyyüp, Er, Duygu   +8 more
core   +1 more source

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

Foveal and Macular Thickness Evaluation by Spectral OCT SLO and Its Relation with Axial Length in Various Degree of Myopia [PDF]

Journal of Clinical and Diagnostic Research, 2015
Purpose: To evaluate the foveal and macular thickness in various degrees of myopia and its association with axial length in low, moderate and high degrees of myopia. Design: A cross-sectional study was done in the Department of Ophthalmology, MGMCRI,
Nancy Elizabeth Samuel, Srikanth Krishnagopal   +1 more
doaj   +1 more source

Cyclic GMP in the pig vitreous and retina after experimental retinal detachment [PDF]

, 2008
Purpose: Earlier studies have revealed a decreased level of cGMP in vitreous fluid obtained from patients with a retinal detachment. To further investigate this phenomenon, we developed an experimental retinal detachment model in pigs.
Heij, E.C., La, La Heij, Ellen C, Diederen, R., Diederen, Roselie M H, Lemmens, Marijke A M, de Vente, Jan, De Vente, J., La Heij, E.C., Lemmens, M.A.M., Kijlstra, Aize, Vente, J., De, Hendrikse, F., Hendrikse, Fred, Kijlstra, A.   +13 more
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