Results 111 to 120 of about 92,391 (275)

Protein Corona Engineering of Lipid Nanoparticles Enables Efficient Functional Gene Silencing in the Liver

open access: yesSmall, EarlyView.
By shaping the protein corona, lipid composition directs LNP tropism and enables the preferential delivery of a TIMP1‐targeting siRNA to liver macrophages. In a murine model of primary biliary cholangitis, this strategy promoted macrophage reprogramming and attenuated liver fibrosis.
Naths G. Sukubo   +15 more
wiley   +1 more source

Pattern classification through fuzzy likelihood

open access: yesLe Matematiche, 2015
This paper introduces a novel way to compute the membership function of a fuzzy set approximating the distribution of some observed data starting with their histogram.
Rosa M. Pidatella   +2 more
doaj  

Multitarget error estimation and adaptivity in aerodynamic flow simulations [PDF]

open access: yes, 2008
Important quantities in aerodynamic flow simulations are the aerodynamic force coefficients including the pressure induced and the viscous stress induced drag, lift and moment coefficients.
Hartmann, Ralf
core  

Deciphering Molecular Charge Anisotropy: The Case of Antibody Solutions

open access: yesSmall, EarlyView.
Molecular charge anisotropy emerges as a key determinant of antibody solution behavior. A multiscale framework combining electrostatic mapping, coarse‐grained simulations, and machine‐learning‐assisted optimization identifies charge patterns that reproduce experimental structure factors and predict collective properties across concentration, revealing ...
Fabrizio Camerin   +4 more
wiley   +1 more source

The Study on Intrinsic Vulnerability of Nitrate in Groundwater in the Lower Reach of Liaohe River Based on WOE Method

open access: yesShuitu baochi yanjiu, 2009
The prediction factor database was constructed by GIS flat according to the analysis of factors which influence the groundwater intrinsic vulnerability in the lower reach of Liaohe River,and then the weight of evidence method was applied to simulate the ...
SUN Cai-zhi, WANG Yan-xin
doaj  

DQN‐Guided Subset‐Induced OCSVM Kernel Approximation for Imbalanced Anomaly Detection

open access: yesIEEJ Transactions on Electrical and Electronic Engineering, EarlyView.
Anomaly detection under limited normal data remains a fundamental challenge due to severe class imbalance and scarcity of anomalies. We propose a novel framework that reformulates support vector selection in One‐Class SVM as a sequential decision‐making problem.
Wenqian Yu, Jiaying Wu, Jinglu Hu
wiley   +1 more source

EE2 and the Fish Brain: Age‐Dependent Impact of 17α‐Ethinylestradiol on Brain Cell Proliferation and Behavior in Sea Bass Larvae

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Endocrine‐disrupting chemicals (EDCs), such as 17α‐ethinylestradiol (EE2), have raised concerns about their potential effects on aquatic organisms, particularly during early developmental stages. In this context, the study of behavioral disruption has gained considerable attention, as it may have consequences on individual fitness and ...
Soloperto Sofia   +6 more
wiley   +1 more source

Adaptive finite elements for viscoelastic deformation problems [PDF]

open access: yes, 2008
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis is concerned with the theoretical and computational aspects of generating solutions to problems involving materials with fading memory, known as
Hill, Harry
core   +1 more source

ALGEBRAIC NONLINEARITY IN VOLTERRA-HAMMERSTEIN EQUATIONS [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 1999
Here a posteriori error estimate for the numerical solution of nonlinear Voltena- Hammerstein equations is given. We present an error upper bound for nonlinear Voltena-Hammastein integral equations, in which the form of nonlinearity is algebraic and ...
doaj  

Good days, bad days: Weather patterns driving bryophyte carbon‐exchange dynamics in tropical rainforest canopies

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract The physiology of tropical mosses, liverworts and lichens may be challenged by the daily weather patterns in lowland rainforests. Since these poikilohydric organisms can only photosynthesize and respire when hydrated, unfavourable timing of light and water availability (
Monica B. Berdugo   +7 more
wiley   +1 more source

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