Results 241 to 250 of about 12,604,595 (306)

RLIM‐associated neurodevelopmental disorders: From clinical spectrum to molecular mechanisms

The FEBS Journal, EarlyView.
RLIM (RNF12) is an E3 ubiquitin ligase essential for mammalian development. Loss‐of‐function variants cause Tønne–Kalscheuer syndrome, while duplications cause Xq13 duplication syndrome, highlighting RLIM dosage sensitivity. This review summarizes the genetics, clinical features, and molecular mechanisms of RLIM‐associated disorders, integrating ...
Madison Landon, Kyra Swildens, Vera M. Kalscheuer, Cristina Gontan, Francisco Bustos   +4 more
wiley   +1 more source

Feasibility, Safety, and Efficacy of Pulsed Field Ablation for Ventricular Arrhythmias: Insights From a Large Health System Registry in the United States

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Pulsed field ablation (PFA) is an emerging non‐thermal ablation modality with proven safety in atrial arrhythmia ablation. However, data on its performance for ventricular arrhythmias (VA) remain limited. Objective To evaluate the feasibility, safety, and efficacy of PFA for complex VA in a multicenter real‐world US registry ...
Narut Prasitlumkum, Juan F. Rodriguez‐Riascos, Hema Vemulapalli, Aakash Somappa, Camilo A. Estrada‐Vargas, Olubadewa A. Fatunde, Carlos A. Rojas, Poojan Prajapati, Keerthika Vijayakumar, Suraj Kapa, Duy Nguyen, Samuel Asirvatham, Malini Madhavan, Christopher McLeod, Hicham Z. El Masry, Abhishek J. Deshmukh, Danesh K. Kella, Ammar M. Killu, Siva K. Mulpuru, Mayank Sardana, Luis R. Scott, Alan M. Sugrue, Komandoor Srivathsan   +22 more
wiley   +1 more source

Optimizing surgery in hidradenitis suppurativa

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Surgery in hidradenitis suppurativa should be matched to disease extent. A structured six‐step approach—comprehensive assessment, optimal timing, ultrasound‐guided mapping, tailored intervention, individualized reconstruction and structured wound care—integrated with targeted systemic therapy optimizes outcomes and reduces recurrence.
Eva Vilarrasa, Philippe Guillem, Barbara Horváth, Marco Romanelli, Carolin E.Frost, Falk G. Bechara, Øystein Grimstad, Antonio Martorell   +7 more
wiley   +1 more source

Posterolateral and anterolateral approaches to unicondylar posterolateral tibial plateau fractures: A comparative study

Injury, 2013
Lateral tibial plateau fractures that are located posterolaterally are difficult to reduce through an anterolateral surgical approach because of the lack of direct visualisation of the fracture. This study compared the results of unicondylar posterolateral tibial plateau fractures in two patient cohorts: one treated through a posterolateral direct ...
Solomon, L., Stevenson, A., Lee, Y., Baird, R., Howie, D.   +4 more
openaire   +4 more sources

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Posterolateral Approaches to the Craniovertebral Junction

Neurosurgery, 2010
The indications and operative technique for a number of posterolateral approaches to the craniovertebral junction (CVJ) are reviewed.The literature addressing posterolateral approaches to the CVJ is reviewed, and illustrative cases are presented.The far lateral approach and its variants, including the transcondylar, supracondylar, and paracondylar ...
Youssef R, Karam, Arnold H, Menezes, Vincent C, Traynelis   +2 more
openaire   +2 more sources

Interpeduncular Sulcus Approach to the Posterolateral Pons

World Neurosurgery, 2020
In this article, we describe a new safe entry point for the posterolateral pons.To show the adjacent anatomy and measure the part of the interpeduncular sulcus that can be safely accessed, we first performed a review of the literature regarding the pons anatomy and its surgical approaches.
Sergio, Cavalheiro, Juan Leonardo, Serrato-Avila, Richard Gonzalo, Párraga, M D S, Da Costa, Jardel Mendoça, Nicácio, Paulo Ricardo, Rocha, Feres, Chaddad-Neto   +6 more
openaire   +2 more sources

Limited Added Value of the Posterolateral Approach

Journal of Knee Surgery, 2015
Posterolateral tibial plateau fractures (AO/OTA 41-B or 41-C) represent a minority of proximal tibia fractures. Numerous surgical approaches have been described, each with unique variations and limitations. The purpose of this study is to quantitatively and qualitatively compare the surface area and structures exposed by four surgical approaches to the
Sarah N, Pierrie, Luke S, Harmer, Madhav A, Karunakar, Marc R, Angerame, Erica B, Andrews, Katherine M, Sample, Joseph R, Hsu   +6 more
openaire   +2 more sources

A Modified Posterolateral Approach to the Thoracic Spine

Journal of Spinal Disorders, 1995
We describe a modified technique for posterolateral approach to the thoracic spine and report the use of this procedure in 21 patients. The technique is safe and effective for selected indications. The evolution of the posterolateral or costotransversectomy approach to the thoracic spine has in large part focused on enlarging the exposure to the ...
B D, Ahlgren, H N, Herkowitz
openaire   +2 more sources

Posterolateral approach to tumours of the dorsolumbar spine

Acta Neurochirurgica, 1986
The authors outline the possible approaches to vertebromedullary tumours of the thoraco-lumbar spine using unilateral or bilateral transverso-arthro-pediculectomy and corporectomy. In a personal series of 20 cases. The technique and indications are described and the results.
F, Lesoin, M, Rousseaux, G, Lozes, L, Villette, J, Clarisse, J P, Pruvo, M, Jomin   +6 more
openaire   +2 more sources