Results 131 to 140 of about 752,743 (348)
Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal +16 morewiley +1 more sourcePoster presentation [PDF]
Surgical and Radiologic Anatomy, 2005 Shomali, T, Hamedi, Somayeh, Yaghoobfar, Akbar, Rezaian, Maryam, Majewski, Mariusz, Calka, Jaroslaw, Skobowiat, Cezary, Stanciulescu, Razvan, Pantu, Cosmin, Enyedi, Mihali, Tarta, Eugen, Filipoiu, Florin Mihail, Hedley, Gil, Benninger, Brion, D'Herde, Katharina, Kerckaert, Ingrid, Verstraete, Koenraad, Audenaert, Emmanuel, Gomes, Germano T, Van Hoof, Tom, Davari, Mohammad Hossein, Hassanzade, Mohamad Mahdi, Amini, Abdollah, Soleimani, Mansooreh, Maghoul, Shahin, Hosseini, Melina, Jafar-Kazemi, Koroush, Nasiri, Ebrahim, Can, Mehmet Ali, Bayram, Sule Biyik, Korkmaz, Ozgur, Bozkus, Ferdi Sefa, Kaygusuz, Mehmet Akif, Balioglu, Mehmet Bulent, Koebke, Jürgen, Komurcu, Mahmut, Ozboluk, Sener, Kurklu, Mustafa, Dinc, Gulten, Akkin, Salin Murat, Roghani, Mehrdad, Joghataie, Mohammad Taghi, Rasoolijazi, Homa, Denk, C Cem, Sargon, Mustafa F, Mocan, Burce Ozgen, Tatar, Emel Cadalli, Tatar, Ilkan, Celik, H Hamdi, Papadopoulos, Nikolaos, Anagnostopoulou, Sophia, Skandalakis, Panagiotis, Douvetzemis, Stergios, Piagkos, Giannoulis, Aikaterini, Vassiliki Kouki, Piagkou, Maria, Gholami, Mohammad Reza, Nezhad, Dariush Bijan, Zhaleh, Mohsen, Javadnia, Fatemeh, Gharravi, Anneh Mohammad, Saba, Mohamad, Abarghoeai, Parviz Raygan, Vaghefy, Raena Eftekhar, Eftekhar Vaghefy, Seyed Hasan, Vaghefi, Raena Eftekhar, Kohestani, Hamid Reza, Poraboli, Ali, Mahmodi, Abolghasem Amir, Eftekhar Vaghefi, Seyed Hasan, Abarghoeai, Parviz Rayegan, Abarghoeai, Roozbeh Rayegan, Kohestani, Hamid, Poya, Fateme, Moshkdanian, Ghazale, Eftekhar Vaghefi, Seyd Hasan, Zargarpoor, Rosa, Ghaem, Reza Montazer, Meibodi, Mohamad Ali Emami, Rayegan, Parviz, Ogut, Tahir, Akkin, Salih Murat, Ustundag, Sinan, Ayhan, Egemen, Nikzad, Hossein, Chegini, Hamidreza, Karacan, Kezban, Kosar, Mehmet Ilkay, Monabati, Ahmad, Mazaheri, Zohreh, Talaei, Tahereh, Namavar, Mohamad Reza, Berjis, Nezamedin, Naderian, Homayoun, Khanlarkhani, Neda, Abolidokht, A, Rajabalian, Saeed, Mousavi, A, Dabiri, Shahryar, Soroure-Azimzadeh, Behzad, Deilami, Masood, Latifpour, Mastafa, Nematollahi-Mahani, Seyed Noureddin, Sheibani, Vahid, Mohammadi, Abbas, Eftekharvaghefi, Seyed Hasan, Ebrahimzadeh, Alireza, Hassanzadeh Taheri, Mohammad Mehdi, Asgari, Alireza, Nourani, Mohammad Reza, Jamalpour, Zahra, Moaiery, Ardesheer, Elian, Amir Hossein, Dalili, Naser, Ahmadpoor, Mahmood Erfanian, Mahmoudian, Alireza, Kermanian, Fatemeh, Selthofer, Robert, Mrcela, Tomislav, Leksan, Igor, Prapa, Stamatia, Konstantinidi, Maria, Mitsaki, Charikleia, Francisco, Margarida, Hainoglou, Roxani, Sianou, Kyriaki, Mitsakis, Menelaos, Anastasiou, Aikaterini, Mitsakis, Ioannis, Haghparast, Elham, Khazei, Majid, Hami, Javad, Akbari, Asghar, Ghiasi, Fateme, Moodi, Hesam, Cimen, Mehmet, Erdil, F Hayat, Gumus, Cesur, Sabanciogullari, Vedat, Mazoochi, Tahereh, Ozbakir, Cemal, Cilingiroglu, Serpil, Ashwood, Neil, Fogg, Quentin, Loukas, Marios, Tubbs, R Shane, Radic, Radivoje, Nikolic, Vasilije, Jo-Osvatic, Ana, Krmek, Nikola, Krmek, Vlado, Veragara, Maria Elena, Cirillo, Angela, Freire, Diego, Sirilo, Angela, Rivara, Alvaro, Soria, Víctor, Almirón, Carina, Vergara, María Elena, Doassans, Inés, Poumayrac, Marie Catherine, Laza, Sebastián, Kachap, Mokhtar Jafarpoor, Javad, Hami, Ashrafi, Ali Reza, Ashrafi, Alireza, Amani, Zahra, Sheverdin, Vadim, Kim, Hyun-Ju, Sadeghimehr, Mohsen, Ashrafi, H R, Amani, A, Hosseini, Mohammad, Hosseinipanah, Seyed Mohammad, Abbasi, Hamed, Kim, Hyeon-Cheol, Park, Jong-Tae, Choi, Jong-Hoon, Kim, Hyun-Joo, Hong, Hee-Suk, Kim, Da-Hye, Celbis, Osman, Ulucam, Enis, Hur, Mi-Sun, Kim, Soo-Young, Kim, Soon-Heum, Choi, Hyun-Gon, Hwang, Eu-Na, Koh, Ki-Seok, Song, Wu-Chul, Kim, Yoo-Ri, Lee, Jeong-Yong, Lee, Ju-Young, Lee, Jae-Gi, Won, Sung-Yoon, Yang, Hun-Mu, Harma, Ahmet, Karakas, Hakki Muammer, Alicioglu, Banu, Gharravi, Annen Mohammad, Karagoz, Huseyin, Kapitonova, Marina Yurievna, Lovasova, Kvetuse, Nezhadi, Akram, Valderrama-Canales, Francisco, Ortug, Gursel, Nazhvani, Seifollah Dehghani, Nazhvani, Fatemeh Dehghani, Cavdar, Safiye, Cakmak, Yusuf Ozgur, Garzon, I, Ozkan, Derya, Pavlova, Velichka, Ogeturk, Murat, Selekler, Macit +214 moreopenaire +10 more sourcesPARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi +13 morewiley +1 more sourcePhenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer +9 morewiley +1 more source
