Results 71 to 80 of about 406,356 (305)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

The management of English language support in postgraduate business education: the CEM model (contextualisation, embedding and mapping) [PDF]

open access: yes, 2009
The paper documents the background, research and preliminary findings relating to a key area emerging in higher education institutions in the UK: providing academic language and study skills to support international students in parallel with their study ...
Porter, Elizabeth, Sloan, Diane
core   +1 more source

Productive Thinking in Postgraduate Students

open access: yesمجلة العصر للعلوم الانسانية والاجتماع, 2023
The study investigates the problem of unproductivity of thinking of some postgraduate students which is attributed to their deactivation of thinking skills in general and productive thinking skills in particular. The problem starts in primary stages up to the higher stages, as confirmed by Saadeh (2009).
null Sawsan Jamal Jawad   +1 more
openaire   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

The Impact of Demographic Characteristics and Risk Tolerance on Investors’ Risk Perception and Portfolio Management

open access: yesThe Lahore Journal of Business, 2014
Behavioral finance focuses on psychological factors—such as risk perception and portfolio management—that play a crucial role in investors’ financial decisionmaking. This study investigates the effect of risk tolerance and demographic characteristics on
Taqadus Bashir   +4 more
doaj  

Groupwork assessments and international postgraduate students : reflections on practice [PDF]

open access: yes, 2004
Groupwork is a common learning and assessment method in Business Schools throughout the UK. It has recognised pedagogic benefits, increases active or deep learning of a subject and, although it often appears to be unpopular amongst students, for these ...
Bamford, Jan
core  

Expectations of postgraduate nursing students: an inquiry

open access: yesCurationis, 2008
Postgraduate supervision in South Africa currently takes place in the context of university transformation with a notable increase in concern for quality. The latter is determined by the extent to which students’ expectations within a supervisory practice are met.
openaire   +5 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Short Communications: Basic Sciences

open access: yesRUHS Journal of Health Sciences, 2023
Postgraduate Students
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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