NGX-4010, a capsaicin 8% patch, for the treatment of painful HIV-associated distal sensory polyneuropathy: integrated analysis of two phase III, randomized, controlled trials [PDF]
BACKGROUND HIV-associated distal sensory polyneuropathy (HIV-DSP) is the most frequently reported neurologic complication associated with HIV infection.
Brew, Bruce J +9 more
core +1 more source
Immunosenescence: Molecular Mechanisms, Diseases, and Therapeutic Innovations
Along with organismal aging or pathogenic processes especially tumor, multiple immune cell types exhibit those well‐established hallmarks of cellular senescent phenotype, mainly characterized by irreversible cell cycle arrest, metabolic disorder, and over production of SASP.
Ninghan Gong +8 more
wiley +1 more source
Clinical observation on radiant shock wave in the treatment of postherpetic neuralgia
Objective To evaluate the effect of radiant shock wave therapy (RSWT) on postherpetic neuralgia. Methods Twenty-six cases of postherpetic neuralgia were treated with RSWT around the pain point.
Xiao-hua LIU +3 more
doaj
The Comparison of Gabapentin and Amitriptilin Effectivity as Pain Therapy in Herniated Nucleus Pulposus [PDF]
Herniated nucleus pulposus (HNP) is one of peripheral neuropathic pain. Although concensus guidelines for the treatment of neuropathic pain are based on the results of the RCT studies, there are still gaps in the literatures.
Cahyaningsih, I. (Indriastuti) +2 more
core
Real-World Treatment of Post-herpetic Neuralgia with Gabapentin or Pregabalin [PDF]
BACKGROUND AND OBJECTIVES: There are limited data examining the real-world use of gabapentin and pregabalin for the treatment of post-herpetic neuralgia (PHN).
Laura Becker +3 more
core +1 more source
A Replicable and Generalizable Neuroimaging‐Based Indicator of Pain Sensitivity Across Individuals
Humans differ in their sensitivity to pain. With six large and diverse fMRI datasets (total N = 1046), this study finds that such individual differences in pain sensitivity can be tracked by fMRI responses to painful stimuli. A highly generalizable machine learning model is further built to predict pain sensitivity across all datasets and analgesic ...
Li‐Bo Zhang +7 more
wiley +1 more source
Gabapentin enacarbil extended release for the treatment of postherpetic neuralgia in adults
Ben M Thomas,1 Paul Farquhar-Smith2 1Chelsea Westminster Hospital, London, UK; 2Department of Anaesthetics, The Royal Marsden NHS Foundation Trust, London, UK Abstract: The development of biomedical technology is allowing refinement of drug therapies in ...
Thomas BM, Farquhar-Smith P
doaj
Impaired Modulation of Pain in Patients with Postherpetic Neuralgia
BACKGROUND: The efficiency of inhibitory pain descending pathways (evaluated using conditioned pain modulation [CPM]) has not been studied in postherpetic neuralgia (PHN).
Gisèle Pickering +4 more
doaj +1 more source
Herpesvaricellae-zoster virus (VZV) on alfaherpesviiruste hulka kuuluv kaheahelaline DNA-viirus, mis põhjustab inimestel primaarinfektsioonina tuulerõugeid (varicella) ja sekundaarse infektsioonina vöötohatist (herpes zoster).
Puis, Liis
core +2 more sources
ABSTRACT Background and Objective Neuropathic pain (NeP) is a common and debilitating consequence of several neurological conditions. Gabapentinoids are used on a large scale for the treatment of both central and peripheral NeP. Mirogabalin, a novel gabapentinoid, has been proposed as a promising treatment for this condition; however, its efficacy and ...
Rafael Batista João +4 more
wiley +1 more source

