Results 91 to 100 of about 5,946 (190)
Effects of RANKL-Targeted Therapy in Immunity and Cancer. [PDF]
, 2014 The role of the receptor activator of nuclear factor-κB ligand (RANKL)/RANK system is well characterized within bone, where RANKL/RANK signaling mediates osteoclastogenesis and bone resorption.
Cheng, Michael L, Fong, Lawrence
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Vedolizumab: an α4β7 integrin antagonist for ulcerative colitis and Crohn’s disease [PDF]
, 2015 Ulcerative colitis (UC) and Crohn’s disease (CD) are chronic, relapsing inflammatory bowel diseases associated with significant morbidity. Conventional therapies for these diseases include corticosteroids, aminosalicylates, immunomodulators, and ...
Biogen Idec Inc +6 more
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Number of Patients Studied Prior to Approval of New Medicines: A Database Analysis [PDF]
, 2013 Background: At the time of approval of a new medicine, there are few long-term data on the medicine's benefit-risk balance. Clinical trials are designed to demonstrate efficacy, but have major limitations with regard to safety in terms of patient ...
Boer, A.C. (Anton) de +5 more
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Evaluation of pregnancy outcomes in patients with multiple sclerosis after fingolimod exposure [PDF]
, 2018 Background and Methods: Limited data are available on the safety of fingolimod in pregnant women. We estimated the risk of adverse pregnancy outcomes in women with multiple sclerosis (MS) exposed to fingolimod either shortly before or during pregnancy in
Butzkueven, Helmut +7 more
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Drug, Healthcare and Patient Safety, 2015 Olaf GJ Naether,1 Andreas Tandler-Schneider,2 Wilma Bilger3 1Reproductive Endocrinology, MVZ Fertility Center Hamburg, Hamburg, 2Center for Reproductive Medicine, Fertility Center Berlin, Berlin, 3Medical Affairs, Fertility, Endocrinology and General ...
Naether OGJ +2 more
doaj
Biosimilars: potential implications for clinicians
Clinical, Cosmetic and Investigational Dermatology, 2016 Misty G Eleryan,1 Sophia Akhiyat,2 Monica Rengifo-Pardo,1 Alison Ehrlich,1,2 1Department of Dermatology, The George Washington Medical Faculty Associates, 2George Washington University School of Medicine & Health Sciences, Washington, DC, USA ...
Eleryan MG +3 more
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A Proactive Approach to Womens Concerns: Womens Longevity Groups and Funds [PDF]
, 2005 With the exception of ten countries in the world, according to the World Health Organization's 2005 report, women outlive men. In the United States, women outlive men by 5.3 years.
Myrna I. Lewis
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Considering the New REMS Legislation of the 2007 Amendments [PDF]
, 2012 On September 27, 2007, the Congress passed new amendments to the Food, Drug and Cosmetic Act. These amendments contained numerous changes to the act aimed at addressing the current needs for food, drug, and cosmetic safety. Yet, arguably one area of that
Walker, Petal
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Revista Médica Electrónica, 2011 La presente investigación caracterizó las notificaciones de sospechas de reacciones adversas medicamentosas en personas mayores de 60 años, recibidas en la Unidad Coordinadora Provincial de Farmacovigilancia, desde el 1 de enero de 2005 al 31 de ...
Leidy Santos Muñoz +1 more
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Authorisation and Withdrawal of Pharmaceutical Innovations in the European Union and in the United States (1995-2003) [PDF]
This is a comparative study of the average and median approval times for pharmaceutical innovations (new molecular entities -NMES- and new biologics), authorised in the United States (US) and in the European Union (EU) under the centralised procedure ...
Cabiedes Miragaya, Laura
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