Results 51 to 60 of about 600,809 (212)
Trends and characteristics of accidental and intentional codeine overdose deaths in Australia [PDF]
, 2015 Examines trends in codeine-related mortality rates in Australia, and the clinical and toxicological characteristics of codeine-related deaths. Abstract Objectives: To examine trends in codeine-related mortality rates in Australia, and the clinical and ...
Amanda Roxburgh +6 more
core +1 more source
Population scale data reveals the antidepressant effects of ketamine and other therapeutics approved for non-psychiatric indications. [PDF]
, 2017 Current therapeutic approaches to depression fail for millions of patients due to lag in clinical response and non-adherence. Here we provide new support for the antidepressant effect of an anesthetic drug, ketamine, by Inverse-Frequency Analysis of ...
Abagyan, Ruben +3 more
core +2 more sources
Postmarketing surveillance is needed [PDF]
BMJ, 2004 EDITOR—The drug point by Harrison-Woolrych and Clark on nose bleeds associated with risperidone highlights a real need for effective communication in the medical fraternity.1 The problem with doctors is that they are quite enthusiastic in prescribing new drugs. …
openaire +2 more sources
Antipsychotics and Torsadogenic Risk: Signals Emerging from the US FDA Adverse Event Reporting System Database [PDF]
, 2013 Background: Drug-induced torsades de pointes (TdP) and related clinical entities represent a current regulatory and clinical burden. Objective: As part of the FP7 ARITMO (Arrhythmogenic Potential of Drugs) project, we explored the publicly available US ...
A Bate +53 more
core +3 more sources
Incomplete Resolution of Deep Vein Thromboses during Rivaroxaban Therapy. [PDF]
, 2017 We present the case of a patient with a deep vein thrombosis (DVT) who failed rivaroxaban therapy. Our patient initially presented with left lower extremity edema, erythema, and pain.
Adashek, Jacob +6 more
core +5 more sources
Scientific Reports, 2020 The World Health Organization estimates the number of people suffering from depression to be over 264 million. Current monoamine transmission modulating therapeutics, even with proper adherence and acceptable tolerability, are not effective for nearly ...
T. Makunts, M. A. Wollmer, R. Abagyan
semanticscholar +1 more source
Improving Drug Safety: The Importance of Postmarking Drug Surveillance [PDF]
, 2004 Improved postmarketing surveillance system may reduce the number of adverse reactions to prescription drugs that under the current system continue to rise as the number of prescriptions written in the U.S ...
James Nyberg, Robert N. Butler
core
Mood, Personality, and Behavior Changes During Treatment with Statins: A Case Series. [PDF]
, 2015 Psychiatric adverse drug reactions (ADRs) have been reported with statin use, but the literature regarding statin-associated mood/behavioral changes remains limited.
Cham, Stephanie +2 more
core +1 more source
EDDA Study Designs Taxonomy (version 2.0) [PDF]
, 2016 The EDDA Study Designs Taxonomy (v2.0) was developed by the Evidence in Documents, Discovery, and Analytics (EDDA) Group: Tanja Bekhuis (Principal Scientist); Eugene Tseytlin (Systems Developer); Ashleigh Faith (Taxonomist); Faina Linkov (Epidemiologist).
Bekhuis, Tanja, Tseytlin, Eugene
core +1 more source
Postmarketing surveillance of captopril for hypertension. [PDF]
British Journal of Clinical Pharmacology, 1992 1. A scheme for augmented spontaneous reporting of adverse drug events using advanced view data systems was developed and applied to study 67,698 consecutive patients prescribed captopril in general practice for the treatment of hypertension. 2. Captopril was an effective hypotensive agent in this population, as only 1.9% of patients were withdrawn ...
D Chalmers, D H Lawson, A Whitehead
openaire +3 more sources