Results 151 to 160 of about 175,299 (292)

WISDOM: history and early demise - was it inevitable?

open access: yes, 2007
In 1989, the UK Medical Research Council (MRC) agreed that, if feasible, a randomized controlled trial to assess the long-term risks and benefits of hormone replacement therapy (HRT) was a priority.
Darbyshire, J, Meade, T, Vickers, M
core   +1 more source

Pregnenolone Reduces L‐Dopa‐Induced Dyskinesias in Female Parkinsonian Monkeys

open access: yesMovement Disorders, EarlyView.
Pregnenolone is the first neurosteroid synthesized from cholesterol in the brain. Ovariectomized female monkeys were tested as a model of women in menopause. They were lesioned with MPTP modeling Parkinson's disease and treated with levodopa (L‐dopa) to induce dyskinesias.
Mélanie Bourque   +5 more
wiley   +1 more source

Long-term trends in the longevity of scientific elites: evidence from the British and the Russian academies of science.

open access: yes, 2011
National science academies represent intellectual elites and vanguard groups in the achievement of longevity. We estimated life expectancy (LE) at age 50 of members of the British Royal Society (RS) for the years 1670-2007 and of members of the Russian ...
Andreev Evgeny M.   +23 more
core   +1 more source

The Influence of Preoperative Urodynamics on Management in Women With Pelvic Organ Prolapse

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Importance The role of preoperative urodynamic studies (UDS) in women undergoing pelvic organ prolapse (POP) surgery remains controversial, especially regarding their influence on surgical planning and patient counseling. Objective To evaluate the impact of preoperative UDS on changes in surgical management and counseling among women with ...
Apisith Saraluck, Jittima Manonai
wiley   +1 more source

Serum markers of bone fragility in type-2 diabetes mellitus [PDF]

open access: yes, 2019
Patients with type-2 diabetes mellitus (T2DM) have normal or increased bone mineral density (BMD) but despite that, they are characterized by an increased hip and vertebral fracture risk that involves the alteration of bone quality and not the reduction ...
Dănciulescu Miulescu, Rucsandra   +5 more
core   +1 more source

A geriatrician's approach to managing the complex older adult with obesity

open access: yesObesity, EarlyView.
Abstract The prevalence of obesity in older adults is rapidly increasing due to the demographic shift occurring globally. Older adults with obesity face health care challenges due to multimorbidity, functional dependency, and disability. This population often has prior history of struggles through weight‐loss attempts during the middle years of life ...
Shenbagam Dewar
wiley   +1 more source

Dose-response relationship between carotenoid intake and risk of depressive symptoms in postmenopausal women

open access: yesFrontiers in Psychiatry
BackgroundIt is well known that postmenopausal women have an increased risk of depression, and there is a dose correlation between carotenoid intake and depression.
Xuexue Li, Su Wang
doaj   +1 more source

Risk for cancer after bariatric surgery compared with the general population: a nationwide matched cohort study

open access: yesObesity, EarlyView.
Abstract Objective Our objective was to evaluate how the incidence of cancer after metabolic and bariatric surgery (MBS) compared with the general population. Methods A nationwide cohort of patients who underwent MBS in Sweden from 2007 to 2020 were matched (age, sex, area of residence) to controls from the general population.
Erik Stenberg   +4 more
wiley   +1 more source

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