Results 41 to 50 of about 4,489,749 (308)

Study of comparison between autonomic dysfunction and dyslipidemia in healthy postmenopausal women

Journal of Mid-Life Health, 2017
Background: Obesity, physical inactivity, and altered estrogen levels play an important role in contributing to disease risk profile and autonomic dysfunction in healthy postmenopausal women.
Kavyach Yalamudi
doaj   +1 more source

Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis

Advanced Science, EarlyView.
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa, Silke De Vriendt, Lixian Liu, Thalles Fernando Rocha Ruiz, Hugo Vankelecom, Christiani Andrade Amorim   +5 more
wiley   +1 more source

Lack of association of ovariectomy-induced obesity with overeating and the reduction of physical activities

Biochemistry and Biophysics Reports, 2019
Obesity commonly occurs in postmenopausal women, increasing the risk of various diseases. Estrogen can prevent obesity by activating lipid metabolism and suppressing depressive behavior.
Eiji Nishio, Takanori Hayashi, Masashi Nakatani, Noriko Aida, Risa Suda, Takuma Fujii, Toru Wakatsuki, Shinichiro Honda, Nobuhiro Harada, Yohei Shimono   +9 more
doaj   +1 more source

A Association between Anthropometric Measurements and some Biochemical Parameters in Premenopausal and Postmenopausal Women

Wasit Journal for Pure Sciences, 2023
: Numerous physiological and biochemical changes are linked to menopause. The current study was intended to examine the transforms linked to anthropometric measurements and bone-related factors.
Maha jamal Frayyeh, Makarim Q. D. Al-Lami   +1 more
doaj   +1 more source

WTAP Transcriptional Suppression by KLF9 Drives Osteoclastogenesis via M6A‐Mediated Regulation of CSF1R Signaling in Estrogen‐Deficient Osteoporosis

Advanced Science, EarlyView.
Scheme of the KLF9/WTAP/YTHDF2/m6A/CSF1R regulatory axis in osteoclastogenesis and estrogen‐deficient osteoporosis. WTAP‐mediated m6A modification of Csf1r mRNA governs osteoclastogenesis via a YTHDF2‐mediated pathway. Pathological upregulation of KLF9 drives Wtap transcription, leading to increased m6A deposition on the 3’‐UTR of Csf1r mRNA.
Chen Shen, Xin Liu, Gaoran Ge, Li Xu, Ziyu Zhang, Chang Lv, Hao Xu, Wenhao Li, Yi Qin, Qifeng Sheng, Qihan Wang, Hongxia Li, Jun Zhou, Huilin Yang, Dechun Geng   +14 more
wiley   +1 more source

Osteopenia and inflammation in postmenopausal women

Frontiers in Immunology, 2013
Info Abstract Supplemental Data Export Citation EndNoteReference ManagerSimple TEXT fileBibTexThe Authors in Frontiers Fedra CiccarelliMassimo De MartinisLia GinaldiGoogle Fedra CiccarelliMassimo De MartinisLia GinaldiGoogle Scholar Fedra CiccarelliMassimo De MartinisLia GinaldiPubMed Fedra CiccarelliMassimo De MartinisLia GinaldiRelated Article in ...
Ciccarelli F, DE MARTINIS, MASSIMO MARIA MARCELLO, GINALDI, Lia   +2 more
openaire   +2 more sources

Similarity‐Enhanced Representation Learning of Non‐Canonical Amino Acids for Therapeutic Peptide Modeling

Advanced Science, EarlyView.
Non‐canonical amino acids (ncAAs) enhance peptide therapeutics but remain difficult to model computationally. SinCAA, a similarity‐enhanced pretraining framework, jointly optimizes contrastive learning guided by a novel conformational similarity metric with masked node reconstruction, capturing both functional relationships and chemical identity of ...
Chencheng Xu, Lesong Wei, Jianmin Wang, Yuanpeng Xiong, Ruochi Zhang, Yu Wang, Chao Zha, Qiangcheng Zeng, Xin Gao   +8 more
wiley   +1 more source

Corneal topographic changes in premenopausal and postmenopausal women

BMC Ophthalmology, 2007
Background To asses the effect of menopause on the corneal curvature changes using corneal computerized videokeratography (CVK) in premenopausal and postmenopausal healthy women. Methods Thirty-six postmenopausal women with mean ages of 49.2 (range 39 to
Aytan Hakan, Calıskan Ahmet, Demirturk Fazli, Demir Helin, Aydin Erdinc, Erkorkmaz Unal   +5 more
doaj   +1 more source

Sociodemographic, Anthropometric, Body Composition, Nutritional, and Biochemical Factors Influenced by Age in a Postmenopausal Population: A Cross-Sectional Study

Metabolites, 2023
Postmenopausal aging has become relevant for understanding health during the transition life stages—the aging process being involved in several disturbances of the human condition.
Héctor Vázquez-Lorente, Lourdes Herrera-Quintana, Jorge Molina-López, Beatriz López-González, Elena Planells   +4 more
doaj   +1 more source

Beneficial Body Mass Index for Age‐Related Kidney Function in Males and Females

AGING MEDICINE, EarlyView.
The impact of BMI on age‐related kidney function decline is highly sex‐ and age‐dependent. Normal BMI (18.5–25 kg/m2) is associated with better age‐related kidney function in all‐aged males and females older than 45 years. ABSTRACT Objectives Kidney function declines with aging, leading to a high prevalence of age‐related disease.
Lu Wei, Yao Ma, Xueqi Chen, Xinran Ni, Yu Zhang, Bei Zhu, Qun Zhang, Weihong Zhao   +7 more
wiley   +1 more source