Results 41 to 50 of about 3,365,654 (307)

Study of comparison between autonomic dysfunction and dyslipidemia in healthy postmenopausal women

Journal of Mid-Life Health, 2017
Background: Obesity, physical inactivity, and altered estrogen levels play an important role in contributing to disease risk profile and autonomic dysfunction in healthy postmenopausal women.
Kavyach Yalamudi
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Association of a history of gestational diabetes mellitus with osteoporosis, bone mineral density, and trabecular bone score in postmenopausal women

Diabetology & Metabolic Syndrome, 2023
Background Studies on the association of gestational diabetes mellitus (GDM) with osteoporosis, and bone mineral density (BMD) have been inconsistent.
Boqi Lu, Liping Zhang
doaj   +1 more source

Similarity‐Enhanced Representation Learning of Non‐Canonical Amino Acids for Therapeutic Peptide Modeling

Advanced Science, EarlyView.
Non‐canonical amino acids (ncAAs) enhance peptide therapeutics but remain difficult to model computationally. SinCAA, a similarity‐enhanced pretraining framework, jointly optimizes contrastive learning guided by a novel conformational similarity metric with masked node reconstruction, capturing both functional relationships and chemical identity of ...
Chencheng Xu, Lesong Wei, Jianmin Wang, Yuanpeng Xiong, Ruochi Zhang, Yu Wang, Chao Zha, Qiangcheng Zeng, Xin Gao   +8 more
wiley   +1 more source

Lack of association of ovariectomy-induced obesity with overeating and the reduction of physical activities

Biochemistry and Biophysics Reports, 2019
Obesity commonly occurs in postmenopausal women, increasing the risk of various diseases. Estrogen can prevent obesity by activating lipid metabolism and suppressing depressive behavior.
Eiji Nishio, Takanori Hayashi, Masashi Nakatani, Noriko Aida, Risa Suda, Takuma Fujii, Toru Wakatsuki, Shinichiro Honda, Nobuhiro Harada, Yohei Shimono   +9 more
doaj   +1 more source

Circulating IL-17A Levels in Postmenopausal Women with Primary Hyperparathyroidism

Mediators of Inflammation, 2020
Background. Primary hyperparathyroidism (PHPT) is a common cause of secondary osteoporosis in postmenopausal women. Th17 lymphocytes and the released cytokine IL-17A play an important role in bone metabolism. Th17 cells have been shown to be activated by
E. Dozio, E. Passeri, E. Vianello, S. Palmieri, C. Eller-Vainicher, M. Corsi Romanelli, S. Corbetta   +6 more
doaj   +1 more source

Puerarin‑Loaded pH‑Responsive ZIF‑90 Nanoparticles Ameliorate Osteoporosis via Enhancing H3K18 Lactylation and Suppressing Aberrant Osteoclast Activation

Advanced Science, EarlyView.
Schematic illustration of the mechanism by which ZIF‐90@PU alleviates osteoporosis via H3K18la‐mediated NFATc1 pathway suppression. ABSTRACT Osteoporosis is characterized by dysregulated osteoclast activity, leading to excessive bone resorption and structural damage.
Jiajia Lu, Yue Xi, Sheng Wang, Ye Chen, Jiajie Yang, Xiaojian Shi   +5 more
wiley   +1 more source

A Association between Anthropometric Measurements and some Biochemical Parameters in Premenopausal and Postmenopausal Women

Wasit Journal for Pure Sciences, 2023
: Numerous physiological and biochemical changes are linked to menopause. The current study was intended to examine the transforms linked to anthropometric measurements and bone-related factors.
Maha jamal Frayyeh, Makarim Q. D. Al-Lami   +1 more
doaj   +1 more source

ERα–PADI4–CXCL8 Axis Drives MDSC‐Mediated Immune Evasion in Anaplastic Thyroid Carcinoma

Advanced Science, EarlyView.
MAPK‐driven ligand‐independent ERα activation drives PADI4 transcription and translation. This enzyme then modifies CXCL8 chemokines through citrullination, generating a potent chemoattractant gradient specifically for myeloid‐derived suppressor cells.
Dongdong Zhang, Ying Cai, Junbin Zhang, Jianyong Zhang, Ran Jing, Ming Cai   +5 more
wiley   +1 more source

Osteopenia and inflammation in postmenopausal women

Frontiers in Immunology, 2013
Info Abstract Supplemental Data Export Citation EndNoteReference ManagerSimple TEXT fileBibTexThe Authors in Frontiers Fedra CiccarelliMassimo De MartinisLia GinaldiGoogle Fedra CiccarelliMassimo De MartinisLia GinaldiGoogle Scholar Fedra CiccarelliMassimo De MartinisLia GinaldiPubMed Fedra CiccarelliMassimo De MartinisLia GinaldiRelated Article in ...
Ciccarelli F, DE MARTINIS, MASSIMO MARIA MARCELLO, GINALDI, Lia   +2 more
openaire   +2 more sources