Results 91 to 100 of about 75,138 (262)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Gambaran Histologik Usus Halus Pada Hewan Coba Selama 24 Jam Postmortem [PDF]

, 2017
: Studies about histological changes in small intestine are still very limited. This study was aimed to obtain the histological changes of the small intestine in several time intervals during 24 hours postmortem.
Kalangi, S. J. (Sonny), Theodore, V. J. (Victori), Wangko, S. (Sunny)   +2 more
core  

Relationship between clinical signs and postmortem test status in cattle experimentally infected with the bovine spongiform encephalopathy agent

BMC Veterinary Research, 2010
Background Various clinical protocols have been developed to aid in the clinical diagnosis of classical bovine spongiform encephalopathy (BSE), which is confirmed by postmortem examinations based on vacuolation and accumulation of disease-associated ...
Stack Michael J, Simmons Marion M, Wells Gerald AH, van Winden Steven, Bone Gemma E, Sach Amanda, Sayers A Robin, Konold Timm, Wear Angus, Hawkins Steve AC   +9 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Gambaran Histologik Gaster Pada Hewan Coba Selama 24 Jam Postmortem [PDF]

, 2016
: Studies about postmortem histological changes in stomach is still very limited. This study aimed to obtain histological changes of stomach in several time intervals during 24 hours postmortem. This is a descriptive study using pig as model.
Kalangi, S. J. (Sonny), Lilingan, M. (Megi), Wangko, S. (Sunny)   +2 more
core  

Brain amyloid in preclinical Alzheimer\u27s disease is associated with increased driving risk [PDF]

, 2016
INTRODUCTION: Postmortem studies suggest that fibrillar brain amyloid places people at higher risk for hazardous driving in the preclinical stage of Alzheimer's disease (AD). METHODS: We administered driving questionnaires to 104 older drivers (19 AD, 24
Bernier, Justine N, Carr, David B, Jones, Richard N, Noto, Richard B, Ott, Brian R, Roe, Catherine M, Snyder, Peter J, Yoo, Don C   +7 more
core   +2 more sources

Postmortem Changes in Muscle

Biotechnology & Biotechnological Equipment, 1990
ABSTRACTThe topic of the postmortem period in muscle has a rich history of scientific accomplishment. It is a topic being vigorously pursued at present with new approaches both by seasoned investigators and by a new generation of meat scientists. I must emphasize to you that I am confident it is a topic critically important to improvements in the ...
openaire   +1 more source

Estimation of postmortem interval using thanatochemistry and postmortem changes

Alexandria Journal of Medicine, 2012
AbstractIntroductionEstimation of postmortem interval is an important goal in forensic medicine. After death, many physiochemical changes occur in a regular sequence and can be used to arrive at an approximate time of death. Thanatochemistry is the chemistry of death.
Salam, HodaFouad Abdel, Shaat, Eman Ahmed, Aziz, Manal Hassan Abdel, MoneimSheta, Abeer Abdel, Hussein, Heba Abdel Samie Mohammed   +4 more
openaire   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source