Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao +28 more
wiley +1 more source
Significance of chondrocyte viability in postmortem interval assessments and chondrocyte viability assay. [PDF]
Mihić AG +6 more
europepmc +1 more source
mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim +4 more
wiley +1 more source
Current Understanding and Future Research Direction for Estimating the Postmortem Interval: A Systematic Review. [PDF]
Strete G +3 more
europepmc +1 more source
This study achieves anisotropic thermal expansion tuning in Nd2(Co1‐xFex)17‐yCry compounds via a magnetoelastic strategy. Variable‐temperature synchrotron X‐ray diffraction reveals that increased Fe content induces switchable lattice responses. Compositional control reduces the volume expansion coefficient αV by 20% (x═0.7) and modulates TC (442–625 K),
Jiayuan Li +8 more
wiley +1 more source
Radiomic analysis of postmortem lung changes: a PMCT-based approach for estimating the postmortem interval. [PDF]
De-Giorgio F +7 more
europepmc +1 more source
Architected Inverse Nacre Hydrogels With High Strength and Crack‐Insensitive Toughness
Hydrogels hold promise for biomedical and engineering applications, yet their practical use is fundamentally limited by the strength‐toughness trade‐off and poor fatigue resistance. In this study, a bioinspired inverse nacre architecture constructed via a scalable thermo‐calendering process is introduced, which overcomes these classic limitations ...
Haidi Wu +10 more
wiley +1 more source
Postmortem Interval Estimation Based on the Developmental Patterns of Hemilucilia segmentaria (Fabricius) (Diptera, Calliphoridae) and Peckia (Euboettcheria) anguilla (Curran & Walley) (Diptera, Sarcophagidae): a Case in Southeastern Brazil. [PDF]
Souza CM +4 more
europepmc +1 more source
Highly Flexible and Conformable ZnO/FeGa Magnetoelectric Heterostructures for Skin wound Healing
The magnetic field‐induced electric field generated by a highly flexile ZnO(piezoelectric)/FeGa(magnetostrictive) magnetoelectric heterostructure embedded in the low Young's modulus elastomer PDMS has been used to stimulate the wound healing processes.
Filippos Perdikos +17 more
wiley +1 more source
Comparison of Transcript and Protein Abundance in Human Donor Retinas Support Extending Postmortem Interval From 12 to 18 Hours to Expand the Donor Pool for Biomedical Research. [PDF]
Easton CA +7 more
europepmc +1 more source

