Results 201 to 210 of about 303,058 (265)

Pentoxifylline dose finding trial in preterm neonates with suspected late onset sepsis (PTX‐trial)

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study (PTX‐trial) is to determine the optimal dose of pentoxifylline (PTX) in preterm neonates (gestational age < 30 weeks) with (suspected) late onset sepsis (LONS). Methods The PTX‐trial is a prospective multicentre open‐label sequential dose‐optimization study with an adapted continual reassessment method.
Serife Kurul, H. Rob Taal, Jan Mazela, Ryszard Lauterbach, Irwin K. M. Reiss, Karel Allegaert, Robert B. Flint, Sinno H. P. Simons   +7 more
wiley   +1 more source

Dynamic Regulation of Ferroptosis in a Neonatal Rat Model of Postnatal Hypoxia-Induced Acute Kidney Injury. [PDF]

Antioxidants (Basel)
Liu TH, Chen BH, Lin GH, Chen HH, Chiu HC, Yang CC, Chu YT, Lin CM, Lu WH.   +8 more
europepmc   +1 more source

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe, Lufina Tsirizani, Buyisile Mkhize, Lubbe Wiesner, Gary Maartens, Francesca Conradie, Richard Court, Marian Loveday, Catriona Waitt, Paolo Denti   +9 more
wiley   +1 more source

Zuranolone: A case study in (regulatory) rush to judgement?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove, Milutin Kostic, Barbara Mintzes, Gianna D'Ambrozio, Allen Shaughnessy   +4 more
wiley   +1 more source

Orchestration of Endothelial and Osteogenic Marker Expression During Osteogenesis. [PDF]

Int J Mol Sci
Chen S, Zhao Y, Chen N, Wu X, Zhang L, Jing Z, Qi L, Cai X, Boström KI, Yao Y.   +9 more
europepmc   +1 more source

Priming innate immunity and long-term outcome. [PDF]

Mol Cell Pediatr
Pradler V, Wright CJ, Kazemi-Butterfield N, Glaser K.   +3 more
europepmc   +1 more source

Prenatal Detection of Interatrial Septal Aneurysm With Postnatal Follow-Up: A Rare Pediatric Case of Arrhythmia in a Two-Year-Old Male. [PDF]

Cureus
Taha AK, Khayyal M, Sheta SS, Ismaiel MA.   +3 more
europepmc   +1 more source

Fetal volvulus: is emergency surgery the only option?-a single-center case series and management considerations. [PDF]

Arch Gynecol Obstet
Holweg M, Lieber J, Kagan KO, Wiechers C, Haase B, Delbrück M, Dietzel M, Jhala T, Slavetinsky C, Schmidt A, Fuchs J.   +10 more
europepmc   +1 more source

From Birth to Unintended Pregnancy: Postnatal Contraception Failures in the First Postpartum Year. [PDF]

Cureus
Javed M, Baloch FN, Verma V.
europepmc   +1 more source