Results 251 to 260 of about 5,422,252 (388)

Zuranolone: A case study in (regulatory) rush to judgement?

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove   +4 more
wiley   +1 more source

Impact of Premature Birth and Delayed Cuddling on Maternal Support Needs and Satisfaction With Postnatal Care and Changes in Support Over Time. [PDF]

open access: yesChild Care Health Dev
Fieß A   +10 more
europepmc   +1 more source

The decline of 6‐thioguanine nucleotides is not linked to impaired efficacy or safety of thiopurines in pregnant women with inflammatory bowel disease

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background Thiopurines are used to maintain remission in inflammatory bowel disease (IBD). These drugs are metabolized into 6‐thioguanine nucleotides (6‐TGN), associated with efficacy, and 6‐methylmercaptopurine ribonucleotides (6‐MMPR), associated with adverse drug reactions. Pregnancy has been linked to a shift in thiopurine metabolism, characterized
Dianne G. Bouwknegt   +13 more
wiley   +1 more source

Women's health facility choices for antenatal, delivery, and postnatal care in Eastern Visayas, Philippines. [PDF]

open access: yesFront Glob Womens Health
Choi A   +8 more
europepmc   +1 more source

New opportunities for bioscaffold‐enabled spinal cord injury repair

open access: yesBMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi   +11 more
wiley   +1 more source

COVID-19 mothers' mother-baby bonding, feeding practices, postnatal care experiences in Qatar: A mixed-methods approach. [PDF]

open access: yesEur J Midwifery
Moya Falcon LC   +9 more
europepmc   +1 more source

Calcium retinoate nanoparticle mediated microglial polarization to regulate inflammatory microenvironment for therapy of neuroinflammatory disease

open access: yesBMEMat, EarlyView.
A nano‐drug based on retinoic acid and calcium is developed, which can be rapily endocytosed by microglia and decomposed into small molecule/ion storms in lysosomes. This nano‐drug regulates microglial phenotype switching from M1 to M2 while indirectly guiding neuronal differentiation of endogenous neural stem cells, thereby ameliorating ...
Shuo Zhang   +13 more
wiley   +1 more source

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