Results 171 to 180 of about 1,208,324 (319)

Poorly controlled postoperative pain: prevalence, consequences, and prevention

, 2017
Tong J Gan Stony Brook University, Stony Brook, NY, USA Abstract: This review provides an overview of the clinical issue of poorly controlled postoperative pain and therapeutic approaches that may help to address this common unresolved health-care ...
Gan TJ
core  

ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer

Advanced Science, EarlyView.
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang, Di Cui, Fanzheng Meng, Xu Zhu, Liang Zhu, Liang Wu, Haifeng Hu, Jizhou Wang, Hanhui Yao, Lianxin Liu   +9 more
wiley   +1 more source

Aptamer‐Targeted PrPC Drives Colorectal Cancer Metastasis via a LYN‐STAT3 Complex and Enables Liquid Biopsy Detection

Advanced Science, EarlyView.
The aptamer WHY‐3E identifies PrPC as a CRC driver. Stabilized by USP18, endocytosed PrPC forms a LYN/STAT3 complex, upregulating MSN transcription to promote metastasis. Crucially, WHY‐3E sensitively detects PrPC‐positive circulating exosomes, establishing a robust theoretical foundation for non‐invasive clinical diagnostics.
Chunlin Wang, Hongyu Wu, Chaojing Zheng, Hao Zhang, Xiaoqiu Wu, Jiaqi Wang, Zewen Chang, Jun Xiang, Yunxiao Liu, Chenkai Zhang, Yuliuming Wang, Hao Jiang, Yuchen Zhong, Jun Luo, Ying Chen, NaNa Zhang, Weiyuan Zhang, Ziming Yuan, ChaoXia Zou, Weihong Tan, Meng Wang, Hanqing Hu, Tao Bing, Guiyu Wang   +23 more
wiley   +1 more source

Protocols for treating the postoperative pain of fractures in Dutch hospitals

, 2013
Rikkert Ossendorp,1 Tymour Forouzanfar,2 Claire E Ashton-James,2,3 Frank Bloemers11Department of Surgery, VU University Medical Center, 2Department of Oral and Maxillofacial Surgery, VU University Medical Center, 3Department of Social and Organizational ...
Bloemers F, Ashton-James CE, Ossendorp R, Forouzanfar T   +3 more
core  

Outcomes of Isolated Femoral Head and Polyethylene Liner Exchange in Revision Total Hip Arthroplasty. [PDF]

Hip Pelvis
Liu J, Daher M, Gilreath N, Sain J, Testa EJ, Smith N, Quinn M, Kayiaros S, Barrett TJ, Antoci V, Cohen EM.   +10 more
europepmc   +1 more source

Noninvasive Characterization of Tumor Heterogeneity in HNSCC: From Clinical Utility to Biological Correlates

Advanced Science, EarlyView.
This study establishes a CT‐based radiomics framework to quantify intratumoral heterogeneity (ITH) in HNSCC. Using unsupervised clustering, tumor ROIs and VOIs are analyzed to calculate 2D/3D ITH scores. The score shows strong predictive value for prognosis and immunotherapy response, and is associated with tumor metabolism and immune microenvironment,
Xinwei Chen, Rui Liu, Yuan Zhou, Yin Xiao, Chengmin Feng, Lin Chen, Yanshi Li, Mengna Wang, Zhaobo Cheng, Yuxi Luo, Long Liu, Lijing Niu, Yue Xiang, Juan Peng, Guohua Hu, Min Pan   +15 more
wiley   +1 more source

Effects of Remifentanil Gradual Withdrawal Combined with Postoperative Infusion on Postoperative Hyperalgesia in Patients Undergoing Laparoscopic hysterectomy: A Factorial Design, Double-Blind, Randomized Controlled Trial

Meng Luo,1,2,* Xue Han,1,2,* Huan Li,1,2 Guangyue Zhou,1,2 Haoxuan Chen,1,2 Fang Gao1,2 1Department of Anesthesiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, People’s Republic of China; 2Jiangsu Province Key ...
Li H, Luo M, Han X, Zhou G, Chen H, Gao F   +5 more
core  

Sublingual sufentanil for postoperative pain relief: first clinical experiences

, 2018
Fleur Meijer,1 Petra Cornelissen,2 Corina Sie,3 Michel Wagemans,4 Anja Mars,5 Tiny Hobma,1,6 Marieke Niesters,1 Albert Dahan,1 J Seppe Koopman,6 Monique AH Steegers2 1Department of Anesthesiology, Leiden University Medical Centre, Leiden, the Netherlands;
Sie C, Hobma T, Wagemans M, Koopman JS, Niesters M, Cornelissen P, Mars A, Steegers MAH, Dahan A, Meijer F   +9 more
core  

BOOI-Defined Obstruction Stratifies Early Outcomes After ThuLEP in Men With Detrusor Underactivity: A Retrospective Complete-Case Cohort Study. [PDF]

Low Urin Tract Symptoms
Ding W, Li L, Liu H, Liu Y, Wang J, Wang Z, Tao L.   +6 more
europepmc   +1 more source

Postoperative antibiotics [PDF]

British Dental Journal, 2004
openaire   +2 more sources