Results 281 to 290 of about 625,252 (337)

TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2

Advanced Science, EarlyView.
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao, Xiaoli Cui, Huizhu Du, Zhuoqun Wang, Chang Liu, Linxin Zhang, Jianing Qi, Di Yang, Hui Yu, Shuang Yan, Wei Liu, Haiming Sun, Mengyang Wang   +12 more
wiley   +1 more source

Bowel Management in Hirschsprung Disease-Pre-, Peri- and Postoperative Care for Primary Pull-Through. [PDF]

Children (Basel)
Lindert J, Schulze F, Märzheuser S.
europepmc   +1 more source

Co‐Treatment With rhBMP‐2 and Rapamycin Modulates Osteogenesis–Adipogenesis Balance to Enhance Aged Bone Regeneration

Advanced Science, EarlyView.
This study demonstrates that the imbalance between osteogenic and adipogenic differentiation in senescent BMSCs, leading to excessive adipocyte accumulation, which subsequently impairs bone regeneration in aged mice. To address this pathological dysregulation, a novel energy‐supplying hydrogel system (PBR) has been developed to restore balanced ...
Zirui He, Xiaoqiao Bai, Fangru Xie, Xuan Wang, Fan Zhang, Yuanman Yu, Yuan Yuan, Changsheng Liu   +7 more
wiley   +1 more source

Enhancing cardiac postoperative care: a smartwatch-integrated remote telemonitoring platform for health screening with ECG analysis. [PDF]

Front Cardiovasc Med
Monteiro R, Rabello GCM, Moreno CR, Moitinho MS, Pires FA, Samesina N, César LAM, Tarasoutchi F, Fernandes F, Martins PCCO, Mariano BM, Soeiro AM, Palhares A, Pastore CA, Jatene FB.   +14 more
europepmc   +1 more source

ROS‐Responsive Wedelolactone Hydrogel Promotes Intervertebral Disc Repair by Disrupting the NF‐κB–LCN2 Inflammatory Feedback Loop

Advanced Science, EarlyView.
A mechanically robust, ROS‐responsive hydrogel is engineered to treat intervertebral disc degeneration by targeting the NF‐κB–LCN2 inflammatory feedback loop. By delivering wedelolactone specifically within oxidative niches, this system disrupts macrophage–disc cell crosstalk.
Zimei Wu, Yan Xu, Lang Qin, Zemin Ling, Yingjie Mai, Xiong Tian Guo, Jiajia Chen, Leping Yan, Lin Wang, Liming Bian, Fuxin Wei   +10 more
wiley   +1 more source

Preoperative preparation and postoperative care in children in thoracic surgery. [PDF]

Turk Gogus Kalp Damar Cerrahisi Derg
Öztürk L, Yiğit H.
europepmc   +1 more source

Studies of granulocyte function (chemiluminescence response) in postoperative infection [PDF]

, 1987
Inthorn, D., Jochum, Marianne, Mühlbayer, D., Redl, H., Redl, H., Schlag, G., Szczeponik, T.   +6 more
core  

Postoperative Care and Outcomes in Solid-Organ Transplant Patients Undergoing Lower Extremity Fracture Treatment. [PDF]

J Orthop Trauma
Chiou D, Mooney BH, Shi B, Upfill-Brown A, Kallini J, SooHoo N, Johnson EE.   +6 more
europepmc   +1 more source

Nursing care in postoperative patient of adnexal cyst in the obstetrics and gynecology service, in a national hospital of Calla

Carmen Elena Martínez Martínez, Pinchi Vasquez Eliska, Sofía Dora Vivanco Hilario   +2 more
openalex   +1 more source

Trends in Anterior Cruciate Ligament Reconstruction Techniques and Postoperative Care Among Leaders in the Field: A Survey of the Herodicus Society. [PDF]

Orthop J Sports Med
Engler ID, Fox MA, Curley AJ, Mohr DS, Dadoo S, Arner JW, Musahl V, Bradley JP.   +7 more
europepmc   +1 more source