Results 71 to 80 of about 943,556 (313)

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

Advanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao, Lijuan Song, Meiqian Xu, Tianhao Liang, Yixuan Chen, Gui Chen, Zaihuan Lin, Huakang Du, Guofei Feng, Zhiming Feng, Qi Zhang, Fan Pan, Saixuan Yang, Xinyin Zhang, Wenxu Peng, Tianlong Li, Zhuoshen Lin, Yabang Chen, Jiayi Liu, Baoxin Peng, Yan Liu, Xing Niu, Ting Li, Chengyu Huang, Ke Mo, Jianlei Xie, Yu Zou, Xiaowen Zhang   +27 more
wiley   +1 more source

Acute Pancreatitis in the Postoperative Course after Esophagectomy: A Major Complication Described in 4 Patients

, 2009
Background: Postoperative pancreatitis is a rare but devastating complication after esophageal surgery. It has been described in connection with abdominal surgery but the etiology in connection with esophageal surgery has never been evaluated.
M. van Heijl, M.I. van Berge Henegouwen, O.R.C. Busch, R.L.G.M. Blom   +3 more
core   +1 more source

A Clinical Study of Decellularized Tissue Engineering Hyaline Cartilage Graft (dLhCG) for Articular Cartilage Repair

Advanced Science, EarlyView.
ABSTRACT Current clinical approaches for knee cartilage repair are often limited by hypertrophy and fibrosis in the regenerated tissues. A decellularized tissue‐engineered hyaline cartilage graft (dLhCG), composed of a type II collagen‐based extracellular matrix, has been developed to overcome this limitation.
Zhen Zhang, Gong Cheng, Wenyong Fei, Qiuzhen Liang, Liang Zhang, Kegui Liu, Jihang Dai, Bo Cong, Xu Hu, Zhonglian Wu, Jialu Zhang, Jinlan Cui, Hang Yao, Dong‐An Wang, Jingcheng Wang, Tao Sun, Jiang Zheng   +16 more
wiley   +1 more source

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

Advanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang, Jiani Deng, Man Yee Cheung, Tingting Fu, Xufeng Qi, Dongqing Cai, Jianmin Sun, Gang Lu, Peng Shi, Wai‐Yee Chan, Xu Li, Hui Zhao   +11 more
wiley   +1 more source

Postoperative delirium in the elderly: diagnosis and management

, 2008
Thomas N Robinson, Ben EisemanDepartment of Surgery, University of Colorado at Denver Health Sciences Center, Aurora, CO, USAbstract: Delirium is a common but often undiagnosed complication in the elderly following a major operation.
Thomas N Robinson, Ben Eiseman
core  

Receiver operator characteristic curve analysis of preoperative risk factors to predict liver resection postoperative severe complication in development group (area under the curve  = 0.898,P<0.0001).

, 2014
Receiver operator characteristic curve analysis of preoperative risk factors to predict liver resection postoperative severe complication in development group (area under the curve  = 0.898 ...
Lunan Yan (407213), Tianfu Wen (120533), Haiqing Wang (160536), Mingqing Xu (120539), Wentao Wang (120529), Jian Yang (12136), Jiayin Yang (142533), Li Jiang (120930), Bo Li (112195)   +8 more
core   +1 more source

Probability of Postoperative Complication after Liver Resection: Stratification of Patient Factors,Operative Complexity, and Use of Enhanced Recovery after Surgery.

, 2021
The current study aimed to assess the performance of the 3-level complexity classification that stratified liver resection procedures into 3 complexity grades (grade I, low; grade II, intermediate; and grade III, high complexity) and to evaluate whether ...
Joliat, G.R., Halkic, N., Kobayashi, K., Demartines, N., Labgaa, Ismail, Schneider, M., Melloul, E., Kawaguchi, Y., Uldry, E., Piazza, G., Gaëtan-Romain Joliat, Nermin Halkic, Yoshikuni Kawaguchi, Nicolas Demartines, Emmanuel Melloul, Giulia Piazza, Ismail Labgaa, Kosuke Kobayashi, Emilie Uldry, Michael Schneider   +19 more
core   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Receiver operator characteristic curve analysis of preoperative risk factors to predict liver resection postoperative severe complication in validation group (area under the curve  = 0.798,P<0.0001).

, 2014
Receiver operator characteristic curve analysis of preoperative risk factors to predict liver resection postoperative severe complication in validation group (area under the curve  = 0.798 ...
Lunan Yan (407213), Tianfu Wen (120533), Haiqing Wang (160536), Mingqing Xu (120539), Wentao Wang (120529), Jian Yang (12136), Jiayin Yang (142533), Li Jiang (120930), Bo Li (112195)   +8 more
core   +1 more source

Multitask Deep Learning Model for Predicting Lymph Node Metastasis and Disease‐Free Survival From Cytology Images in Bladder Cancer: A Multicenter Study With Pan‐Cytology Validation

Advanced Science, EarlyView.
Through self‐supervised pretraining and supervised fine‐tuning on large‐scale cytology image datasets, CytoNet predicts lymph node metastasis and survival. Across independent cohorts, this multitask framework demonstrates robust performance, improves risk stratification beyond radiological assessment, and provides interpretable evidence to support ...
Guibin Hong, Fan Jiang, Ye Xie, Xiaowei Huang, Runnan Shen, Yun Wang, Mengyi Zhu, Haoxuan Wang, Hongkun Yang, Yanxiao Nie, Zhen Lin, Rui Chen, Nengtai Ouyang, Tianxin Lin, Shaoxu Wu   +14 more
wiley   +1 more source