Results 101 to 110 of about 467,341 (320)

Ultrasound‐Triggered Nanocomposite “Lever” Hydrogels with a Full Repair System Accelerates Diabetic Foot Ulcer Repair

open access: yesAdvanced Science, EarlyView.
Ultrasound (US)‐treated nanocomposite ‘lever’ hydrogels reprogrammed wound reactive oxygen species (ROS) levels and promoted wound healing in infected diabetic foot ulcers. Abstract Diabetic foot ulcers (DFUs) are a complex mixture of neuropathy, peripheral arterial disease, and infection, where excessive reactive oxygen species (ROS) exacerbates ...
Yuting Shen   +16 more
wiley   +1 more source

Injectable and Sprayable Thermoresponsive Hydrogel with Fouling‐Resistance as an Effective Barrier to Prevent Postoperative Cardiac Adhesions

open access: yesAdvanced Science, EarlyView.
Postoperative cardiac adhesions lead to numerous difficulties in reoperation procedures. Here, a thermo‐responsive in situ formed hydrogel is shown to can reliably cover the wounds after a convenient spraying or injection and significantly reduce adhesion formation in primary and recurrent cardiac injury adhesion models.
Kun Shi   +11 more
wiley   +1 more source

The Role of MCPIP1 in Macrophage Polarization and Cardiac Function Post‐Myocardial Infarction

open access: yesAdvanced Science, EarlyView.
Following myocardial infarction, MCPIP1 deficiency in macrophages triggers ferroptosis, driving proinflammatory M1 dominance over reparative M2 phenotypes. This imbalance amplifies splenic monocyte release and sustains cardiac inflammation. Concurrently, excessive inflammatory mediators and insufficient TGF‐β impair fibroblast activation, delaying ...
Xingxu Zhang   +8 more
wiley   +1 more source

Polymer Brush‐Based Asymmetric Porous Patch with Excellent Anti‐Bacterial and Anti‐Contamination Properties Enables Infectious Abdominal Wall Defect Repair

open access: yesAdvanced Science, EarlyView.
A zwitterionic asymmetric patch is developed via self‐induced phase separation. The cationic layer exhibits anti‐bacterial efficacy and releases pro‐healing factor, while the zwitterionic hydrogel prevents contamination and visceral adhesion. The strong mechanical interlocking of two layers leads to a high and stable burst pressure tolerance.
Zeping Huang   +11 more
wiley   +1 more source

Gas Bubbles from Biodegradable Magnesium Implants Convey Mechanical Cues and Promote Immune Cell Stimulation

open access: yesAdvanced Science, EarlyView.
Bubbles in soft tissue are the unavoidable consequence of magnesium implant degradation in patients, yet their biological significance remains unclear. Using advanced imaging and spatial transcriptomics, this study reveals a pronounced inflammatory and mechanical response near bubbles, contrasting with pro‐regenerative events closer to the implant ...
Heithem Ben Amara   +3 more
wiley   +1 more source

Intraoperative Fast Adaptive Focus Tracking Robotic OCT Enables Real‐Time Tumor Grading and Large‐Area Microvascular Imaging in Human Spinal Cord Surgery

open access: yesAdvanced Science, EarlyView.
The fast adaptive focus tracking robotic optical coherence tomography (FACT‐ROCT) offers real‐time, high‐resolution imaging of spinal cord tumors during surgery. By reducing motion artifacts with robotics and adaptive focal tracking, it accurately differentiates tumor grades using a novel attenuation coefficient marker and reveals critical ...
Bin He   +16 more
wiley   +1 more source

Chest ultrasound to detect postoperative pulmonary complications after thoracic surgery: a comparative study

open access: yesThe Cardiothoracic Surgeon
Background Patients who underwent thoracic surgery procedures were usually subjected to daily chest X-rays until discharge, exposing patients to ionizing radiation and requiring patient movement with chest drains, difficult positioning, and time ...
Ali Zein Elabdein   +3 more
doaj   +1 more source

Intelligent Perioperative System: Towards Real-time Big Data Analytics in Surgery Risk Assessment [PDF]

open access: yesarXiv, 2017
Surgery risk assessment is an effective tool for physicians to manage the treatment of patients, but most current research projects fall short in providing a comprehensive platform to evaluate the patients' surgery risk in terms of different complications.
arxiv  

Ultrasound‐Responsive Piezoelectric Membrane Promotes Osteoporotic Bone Regeneration via the “Two‐Way Regulation” Bone Homeostasis Strategy

open access: yesAdvanced Science, EarlyView.
Patients with osteoporosis face a higher risk of bone injury, mainly due to weakened osteogenic differentiation and bone formation, along with increased osteoclast differentiation and bone resorption activity, leading to bone homeostasis imbalance.
Xinhui Wu   +13 more
wiley   +1 more source

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