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Alvimopan for postoperative ileus
American Journal of Health-System Pharmacy, 2009The efficacy, safety, pharmacology, pharmacokinetics, drug-drug interactions, and administration of alvimopan for postoperative ileus are reviewed.Alvimopan is a selective mu-opioid receptor antagonist with no central nervous system activity. When orally administered after partial small- or large-bowel resection in patients with primary anastomosis ...
Heather R, Bream-Rouwenhorst +1 more
openaire +2 more sources
Geburtshilfe und Frauenheilkunde, 1987
When the causes and pathophysiology of the various types of ileus are known there are numerous possibilities of preventing them and logical therapeutic approaches, in particular in the case of functional ileus. Careful postoperative monitoring is obligatory!
H, Schmidt-Matthiesen +1 more
openaire +1 more source
When the causes and pathophysiology of the various types of ileus are known there are numerous possibilities of preventing them and logical therapeutic approaches, in particular in the case of functional ileus. Careful postoperative monitoring is obligatory!
H, Schmidt-Matthiesen +1 more
openaire +1 more source
Management of Postoperative Ileus
Orthopedics, 2012Postoperative ileus, a temporary cessation in bowel motility, is a common and significant complication of major surgery. Consequences of postoperative ileus include increased patient discomfort, delayed time to adequate nutrition, prolonged length of stay, and increased cost to the patient and healthcare system. The traditional, multi-modal approach to
Melissa, Thompson, Barbara, Magnuson
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The effect of gum chewing on postoperative ileus in open colorectal surgery patients: A review
Journal of Perioperative Practice, 2020Background Postoperative ileus is a common complication of abdominal surgery, leading to prolonged hospital stay and associated costs. Gum chewing may be a safe, cheap intervention to reduce postoperative ileus.
R. Sammut +3 more
semanticscholar +1 more source
Diseases of the Colon & Rectum, 2004
Postoperatively, some patients experience a prolonged inhibition of coordinated bowel activity, which causes accumulation of secretions and gas, resulting in nausea, vomiting, abdominal distension, and pain. This prolonged inhibition can take days or weeks to resolve and often is referred to as postoperative paralytic ileus lasting more than three days
Mirza K, Baig, Steven D, Wexner
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Postoperatively, some patients experience a prolonged inhibition of coordinated bowel activity, which causes accumulation of secretions and gas, resulting in nausea, vomiting, abdominal distension, and pain. This prolonged inhibition can take days or weeks to resolve and often is referred to as postoperative paralytic ileus lasting more than three days
Mirza K, Baig, Steven D, Wexner
openaire +2 more sources
The American Journal of Surgery, 2001
Postoperative ileus (POI) is an inevitable adverse consequence of surgical procedures. In fact, prolonged POI can lead to patient discomfort, decreased mobility, delayed enteral feeding, and ultimately, prolonged hospitalizations and increased costs.
Kehlet, H, Holte, Kathrine
openaire +2 more sources
Postoperative ileus (POI) is an inevitable adverse consequence of surgical procedures. In fact, prolonged POI can lead to patient discomfort, decreased mobility, delayed enteral feeding, and ultimately, prolonged hospitalizations and increased costs.
Kehlet, H, Holte, Kathrine
openaire +2 more sources
Postoperative Ileus Murine Model
Journal of Visualized ExperimentsMost patients experience postoperative ileus (POI) after surgery, which is associated with increased morbidity, mortality, and hospitalization time. POI is a consequence of mechanical damage during surgery, resulting in disruption of motility in the gastrointestinal tract.
Dan, Tian +8 more
openaire +2 more sources
Neurogastroenterology and Motility, 2018
The cholinergic anti‐inflammatory pathway comprises the perception of peripheral inflammation by afferent sensory neurons and reflex activation of efferent vagus nerve activity to regulate inflammation.
G. Hong +7 more
semanticscholar +1 more source
The cholinergic anti‐inflammatory pathway comprises the perception of peripheral inflammation by afferent sensory neurons and reflex activation of efferent vagus nerve activity to regulate inflammation.
G. Hong +7 more
semanticscholar +1 more source