Results 101 to 110 of about 330,067 (262)

Academia and clinical practice – working together successfully to develop skin integrity knowledge and skills

, 2013
Clinicians often find it difficult to devote sufficient time to develop proposals that will investigate issues that enhance the patient experience. Thus, clinicians need to access researchers and academics who can assist in developing research proposals,
Conway, Barbara R, Conway, Barbara, Fleming, Leigh, Atkinson, Ross, Ousey, Karen   +4 more
core  

O uso profilático da amoxicilina em exodontias de terceiros molares impactados realizadas nas clínicas de Odontologia da UFSC: Estudo clínico randomizado duplo cego [PDF]

, 2013
TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Odontologia.Este estudo clínico randomizado duplo cego objetivou avaliar o efeito da profilaxia com administração de amoxicilina pré-operatória no controle de infecção
Martins, Mariana Saideles
core  

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source

Risk factors for postoperative deep infection in bone tumors

, 2017
Background: Postoperative deep infection after bone tumor surgery remains a serious complication. Although there are numerous reports about risk factors for postoperative deep infection in general surgery, there is only a small number of reports about ...
69864, 多田, 薫, Higuchi, Takashi, 69863, 69862, 69861, Miwa, Shinji, 90332668, 林, 克洋, Kajino, Yoshitomo, 土屋, 弘行, 樋口, 貴史, 80507054, 60622884, 20397186, Hayashi, Katsuhiro, Tada, Kaoru, 70512218, 00728719, Takeuchi, Akihiko, 69860, 阿部, 健作, 40753455, Yamamoto, Norio, 73416, 73415, Taniguchi, Yuta, 73414, 73413, Inatani, Hiroyuki, 73412, 武内, 章彦, 三輪, 真嗣, 90543645, 69859, 69858, 白井, 寿治, Abe, Kensaku, 40227434, Shirai, Toshiharu, Tsuchiya, Hiroyuki, 山本, 憲男, 60749191   +42 more
core   +1 more source

G6PC Downregulation Promotes Renal Calcium Oxalate Stone Formation via Lactate‐Induced SNAIL1 K206 Lactylation and Epithelial‐Mesenchymal Transition

Advanced Science, EarlyView.
In renal calcium oxalate stone formation, G6PC downregulation leads to lactate accumulation. This lactate mediates CBP/p300‐dependent lactylation of SNAIL1 at K206, promoting its nuclear translocation. Nuclear SNAIL1 activates the TGF‐β/SMAD3 pathway, driving epithelial‐mesenchymal transition and fibrosis, which ultimately facilitates crystal ...
Kai Liu, Boming Zhang, Ruixin Fan, Chen Duan, Yangjun Zhang, Huahui Wu, Xiangyang Yao, Xiongmin Mao, Bo Li, Youmiao Zeng, Zhenzhen Xu, Yang Wang, Mengcheng Luo, Xinyu Xu, Ninghan Feng, Heng Li, Hua Xu   +16 more
wiley   +1 more source

Risk of Postoperative Infection in Patients with Inflammatory Bowel Disease [PDF]

, 2006
Background/Aims: The clinical course of patients with inflammatory bowel disease (IBD) frequently leads to the use of immunosuppressants and immunomodulators.
이상길
core  

ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer

Advanced Science, EarlyView.
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang, Di Cui, Fanzheng Meng, Xu Zhu, Liang Zhu, Liang Wu, Haifeng Hu, Jizhou Wang, Hanhui Yao, Lianxin Liu   +9 more
wiley   +1 more source

A Millimeter‐Scale Implantable Magneto–Mechano–Electric Transducer Based on BTO Piezoelectric Ceramics for Remote Wireless Electrical Stimulation of Injured Sciatic Nerves

Advanced Science, EarlyView.
We report a fully wireless, circuit‐free neural stimulator built on a millimetric magneto‐mechano‐electric (MME) cantilever transducer (3 × 10 × 5 mm) with a barium titanate (BTO) piezoelectric ceramic core. Under low‐frequency alternating magnetic fields, the MME cantilever mechanically oscillates, inducing stress on the BTO element and thereby ...
Yijing Wang, Jingyu Tian, Zhe Xu, Cuiling Zhang, Jingen Wu, Ming Liu, Zhilu Ye, Xiaohui Zhang   +7 more
wiley   +1 more source

Wavelength‐Dependent Photobiomodulation Regulates Macrophage Polarization via Mitochondrial Dynamics and Metabolic Reprogramming

Advanced Science, EarlyView.
Light wavelength encodes distinct macrophage fates through mitochondrial and metabolic remodeling. Red 625 nm irradiation induces glycolysis, mitochondrial fission, and M1 polarization, whereas near‐infrared 850 nm irradiation promotes fatty acid oxidation, mitochondrial fusion, and M2 polarization.
Qiusheng Shi, Hao Jia, Jianfei Dong, Linhao Li, Jingqi Cao, Xun Chen, Zhenzhen Jia, Jing Na, Zhijie Yang, Xinyuan Chen, Yubo Fan, Shuhua Yue, Lisha Zheng   +12 more
wiley   +1 more source

Early Postoperative C-Reactive Protein Trajectories After Thoracic Surgery: A Retrospective Cohort Study

Biomedicines
Background: Distinguishing expected postoperative inflammation from early infection remains challenging after thoracic surgery; serial C-reactive protein (CRP) is widely used to aid this differentiation.
Ilker Kolbas, Berivan Karatekin, Esra Ergun Alış, Irfan Cicin   +3 more
doaj   +1 more source