Results 101 to 110 of about 7,376 (201)

Local Anesthetics in Cancer: Mechanisms and Translational Perspectives

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang   +4 more
wiley   +1 more source

Drugs for preventing postoperative nausea and vomiting [PDF]

open access: bronze, 2006
J. B. Carlisle, Carl A Stevenson
openalex   +1 more source

Effect of the rs7858836 Single‐Nucleotide Polymorphisms of the ASTN2 Gene on Pain‐Related Phenotypes in Japanese Women Who Underwent Laparoscopic Gynecologic Surgery

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
Schematic overview of the study examining the association between the ASTN2 rs7858836 T allele and postoperative pain–related phenotypes in humans. The analysis focuses on the relationship between this genetic variant and postoperative pain intensity as well as analgesic responses.
Rie Inoue   +9 more
wiley   +1 more source

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang   +15 more
wiley   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang   +7 more
wiley   +1 more source

Comparison of Efficacy of Dexamethasone and Orogastric Suction in Reducing Post Tonsillectomy Vomiting in Children

open access: yesGomal Journal of Medical Sciences, 2013
Background: The use of gastric suction has been advocated while dexamethasone reduces postoperative vomiting and pain. The objective of the study was to compare effectiveness of gastric suction with an orogastric tube and the effect of a single dose of ...
Raza Muhammad   +4 more
doaj  

Home - About - Disclaimer - Privacy