Results 111 to 120 of about 1,798,300 (303)
When nucleus pulposus cells senesce, PHGDH decreases, reducing serine synthesis and glutathione, impairing antioxidant capacity. The intermediate α‐KG also drops, lowering JMJD3 demethylase activity, increasing H3K27me3 at the Rap1b promoter, and reducing Rap1b expression, whose down‐regulation in turn activates mTORC1 and suppresses autophagy ...
Hao‐Wei Xu +5 more
wiley +1 more source
Effects of Lidocaine on Reducing the Need for Anesthetic Drugs during Ophthalmologic Surgeries
Background: The most common postoperative complications are pain, vomiting, and nausea. They may in turn lead to other complications such as wound damage. On the other hand, the use of opioid analgesics has unwanted effects on patients.
Hassan Ali Soltani +2 more
doaj
The effects of indomethacin, diclofenac, and acetaminophen suppository on pain and opioids consumption after cesarean section [PDF]
Background: Cesarean section is one of the common surgeries of women. Acute post-operative pain is one of the recognized post-operative complications.
Masood Entezariasl +7 more
core +1 more source
Postoperative infectious complications (PICs) have been associated with poor long‐term outcomes after colorectal cancer surgery, but evidence in the modern minimally invasive era remains limited. In this multicenter cohort of 5377 patients undergoing curative resection, PICs were independently associated with worse overall survival and relapse‐free ...
Takehito Yamamoto +7 more
wiley +1 more source
ABSTRACT Laparoscopic surgery is increasingly used to treat colonic diverticulitis; however, its role in emergency, perforated, high‐risk, and procedure‐specific settings remains uncertain. This structured narrative review evaluated and synthesized comparative evidence by clinical setting, operative strategy, and patient risk profile to provide a ...
Marie Hanaoka +4 more
wiley +1 more source
This nationwide observational study used data from the National Clinical Database. Patients who underwent total or distal gastrectomy for gastric cancer after chemotherapy between January 2014 and December 2022 were included. Minimally invasive surgery was associated with lower incidences of overall postoperative complications of Clavien–Dindo grade ...
Nobuaki Hoshino +8 more
wiley +1 more source
Postoperative Pain and Opioid Use in Urogynecology Patients
Opioid use disorder remains a leading national cause of mortality. Physician opioid prescribing contributes to this crisis. In urogynecology, most of these prescriptions are aimed at addressing postoperative pain.
Laura DiVirgilio +2 more
doaj +1 more source
ABSTRACT Small intestinal bacterial overgrowth (SIBO) has recently gained increasing attention as a potential cause of postoperative gastrointestinal symptoms following gastrointestinal cancer surgery. Surgical procedures can disrupt normal gastrointestinal physiology through anatomical reconstruction, impaired motility, reduced gastric acid secretion,
Toru Aoyama +2 more
wiley +1 more source
Incisional hernia remains a common complication after minimally invasive gastroenterological surgery despite small extraction incisions. In this propensity score‐weighted analysis, barbed sutures significantly reduced the incidence of incisional hernia compared with conventional slowly absorbable monofilament sutures without increasing postoperative ...
Shusaku Honma +8 more
wiley +1 more source

