Results 71 to 80 of about 700,225 (313)

Intraoperative methadone for postoperative pain in adult patients undergoing tonsillectomy—a randomised controlled trial

BJA Open
Background: Tonsillectomy is a common procedure often associated with severe postoperative pain. This study hypothesised that methadone would provide superior postoperative pain relief and reduced opioid consumption compared with fentanyl.
Michael Bøndergaard, Peter Gaarsdal Uhrbrand, Tutku Karaca, Marianne Rhode, Thomas Kjærgaard, Rene Thunberg Svendsen, Tejs Ehlers Klug, Lone Nikolajsen, Kristian Dahl Friesgaard   +8 more
doaj   +1 more source

Acetylation Regulates ACSL4 Degradation Through Chaperone‐Mediated Autophagy to Alleviate Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Intervertebral disc degeneration is triggered by ACSL4 accumulation‐mediated ferroptosis of nucleus pulposus cells due to CMA dysfunction. KAT2B promotes ACSL4 degradation via CMA through acetylation. AAV‐mediated LAMP2A delivery or engineered exosomes rescue nucleus pulposus cell senescence and disc degeneration.
Zhouwei Wu, Zhichen Jiang, Chenglong Hong, Shu Yang, Shuqing Jin, Chenyu Wu, Kaijie Guo, Jiang Liu, Shaobo Xu, Chenggui Wang, Xiangyang Wang   +10 more
wiley   +1 more source

Evaluation of Pain Management after Surgery: An Observational Study

Medicina, 2020
Background and Objectives: Choosing a pain management strategy is essential for improving recovery after surgery. Effective pain management reduces the stress response, facilitates mobilization, and improves the quality of the postoperative period.
Regina Sierżantowicz, Jolanta Lewko, Dorota Bitiucka, Karolina Lewko, Bianka Misiak, Jerzy Robert Ładny   +5 more
doaj   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

225 Continuous ultrasound-guided rectus-sheath block for midline laparotomy: an effective postoperative pain management technique – case series [PDF]

, 2021
C Pinto, Francisco Matias
openalex   +1 more source

Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles

Advanced Science, EarlyView.
A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie, Songqi Bi, Bang Su, Rongqi Zhou, Xudong Li, Zhixing Yan, Xiaoyang Zhou, Fanxu Wang, Tiecheng Yu   +8 more
wiley   +1 more source

Pain management after lung surgery

Nursing Reports, 2014
Pain management is an integral challenge in nursing and includes the responsibility of managing patients’ pain, evaluating pain therapy and ensuring the quality of care.
Maria Frödin, Margareta Warrén Stomberg   +1 more
doaj   +1 more source

Postoperative pain management in children: Guidance from the pain committee of the European Society for Paediatric Anaesthesiology (ESPA Pain Management Ladder Initiative)

Paediatric anaesthesia, 2018
The main remit of the European Society for Paediatric Anaesthesiology (ESPA) Pain Committee is to improve the quality of pain management in children. The ESPA Pain Management Ladder is a clinical practice advisory based upon expert consensus to help to ...
M. Vittinghoff, P. Lönnqvist, V. Mossetti, S. Heschl, D. Simić, Vesna Čolović, D. Dmytriiev, Martin Hölzle, M. Zielińska, Anna Kubica-Cielińska, Elizabeth Lorraine-Lichtenstein, I. Budic, Marijana Karišik, B. D. J. María, F. Smedile, N. Morton   +15 more
semanticscholar   +1 more source

A Wearable System Featuring Biomimetic Spatially Distributed Iontronic Sensing Array for Dynamic Monitoring of Deep Tissue Modulus

Advanced Science, EarlyView.
A fully wearable system enables real‐time, dynamic, and accurate monitoring of Young's modulus in multilayer tissues containing deep muscle. It demonstrates high accuracy and robustness across simulations, benchtop validations, and human testing. It quantifies edema severity and tracks muscle stiffness during rest, loaded elbow flexion, rope skipping ...
Zhenning Wang, Chaohua Fang, Ruoyu Sun, Chenghao Feng, Xiaoyuan Wang, Hao Bi, Yidan Wu, Jiangdong Gong, Yuyang Wang, Jiahao Guo, Yu Chang, Huizhi Wang, Tingrui Pan   +12 more
wiley   +1 more source

Pain Management After Spinal Surgery

Indian Journal of Pain, 2015
One of the most important cause of postoperative morbidity is insufficiently treated pain. Patient undergoing spinal surgery often suffer from severe preoperative pain and may require large doses of analgesic drugs including opioids.
A Rudra, Suman Chaterjee, S Ray, S Ghosh
doaj   +1 more source