Results 91 to 100 of about 4,202,493 (246)

In Vivo Direct Reprogramming: Current Progress and Future Prospects from Mechanisms to Therapeutic Application

Advanced Science, EarlyView.
This review examines the potential of in vivo direct reprogramming in regenerative medicine for functional tissue restoration, highlighting the role of tissue‐resident cues in generating functionally mature reprogrammed cells from lineage‐related cells. It contains a discussion on mechanisms, reprogramming factors, delivery approaches, and applications
Rishabh Deo Singh, Mauro Calvoli, Kyeong Kyu Kim   +2 more
wiley   +1 more source

Comparison of costs of home and facility-based basic obstetric care in rural Bangladesh. [PDF]

, 2010
This study compared the costs of providing antenatal, delivery and postnatal care in the home and in a basic obstetric facility in rural Bangladesh. The average costs were estimated by interviewing midwives and from institutional records.
N Sabina, Sabina, N., Killewo, J., J Borghi, Killewo, J, Borghi, J, J Killewo, Ronsmans, C, Borghi, J., Ronsmans, C., Sabina, N, C Ronsmans   +11 more
core   +1 more source

Implementation and Evaluation of Postpartum Midwifery Care at Home at a Federally Qualified Health Center in Washington, DC

Health Equity
Background: The postpartum period is a critical time to support birthing people and infants, address and mitigate perinatal health inequities, and promote joy and connection.
Katie DePalma, Ebony Marcelle, Emma Clark, Teresa O’Brien, Sanjana Chimata, Erica Eliason, Bayyinah Muhammad, Sola Stamm, Nicole Vernot-Jonas, Pawel Olowski, Dawn Sherman, Christina X. Marea   +11 more
doaj   +1 more source

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

Advanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen, Liangxia Jiang, Xianbin Wang, Lili Zhong, Rongcan Luo, Min Su, Liangzhao Chu, Peng Luo   +7 more
wiley   +1 more source

Postpartum visit attendance after spontaneous and medically indicated preterm birth

Pregnancy
Introduction Individuals with preterm birth (PTB) are less likely to attend postpartum visits compared to those with term birth but are more likely to have conditions such as hypertensive disorders.
Kristan Scott, Rachel F. Ledyard, M. Emma Bernstein, Abigail Obeng‐Marnu, Taneisha R. Sinclair, Anne M. Mullin, Celeste Durnwald, Timothy D. Nelin, Heather H. Burris   +8 more
doaj   +1 more source

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

Exploring women's experiences regarding postpartum physical activity: A qualitative research study

, 2021
This research study was about women's experiences regarding postpartum physical activity in Nova Scotia.Although recovery after birth can be promoted through body movement, many women do not engage in postpartum physical activity.
Akbari Nassaji, Neda
core  

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Pilot Trial of Quarterly Text-Based Patient Contacts to Increase Engagement in HIV Care Postpartum: Lessons Learned

Telemedicine Reports
Introduction: In South Carolina, there is a high prevalence of pregnant and postpartum individuals with HIV not engaged in medical care, potentially resulting in higher rates of perinatal transmission. Innovative patient-centered approaches are needed to
Emily Johnson, Jillian Harvey, Katie Kirchoff, Rebecca Verdin, Samantha D’Orio, Kathryn King, Gweneth B. Lazenby   +6 more
doaj   +1 more source

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

Advanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu, Xinyue Luo, Jie Zhao, Ziyan Jiang, Jiayi Zhai, Taomin Zhu, Xueke Jia, Xiaohan Ma, Henghua Jiang, Huimin Li, Yaping Feng, Jin Ke, Xing Long   +12 more
wiley   +1 more source