Results 61 to 70 of about 4,202,493 (246)

Neuropeptide Y—Graphene Oxide Complexes Inhibit Amygdala NPY‐Receptor Expressing Glutamatergic Pathways and Selectively Remove Aversive Memory In Vivo

Advanced Science, EarlyView.
A graphene oxide nanocarrier presents neuropeptide Y specifically to NPY receptor‐expressing pathways in the amygdala, whose activation selectively suppresses aversive memory formation, without modulating anxiety responses. This circuit‐restricted drug release strategy may impact future design of neuropsychiatric therapies with limited off‐target ...
Elisa Pati, Audrey Franceschi Biagioni, Raffaele Casani, Luis M. Arellano, Tommaso Battisti, Gloria Garcia‐Ortega, Neus Lozano, Alberto Bianco, Kostas Kostarelos, Laura Ballerini, Giada Cellot   +10 more
wiley   +1 more source

Plasma oxytocin concentration during pregnancy is associated with development of postpartum depression [PDF]

, 2011
Postpartum depression (PPD) affects up to 19% of all women after parturition. The non-apeptide oxytocin (OXT) is involved in adjustment to pregnancy, maternal behavior, and bonding.
Skrundz, Marta, Marta Skrundz, Irina Nast, Bolten, Margarete, Nast, Irina, Hellhammer, Dirk H., Meinlschmidt, Gunther, Margarete Bolten, Gunther Meinlschmidt, Dirk H Hellhammer   +9 more
core   +1 more source

Identifying a Csmd3+ Microglial Subpopulation that Drives Cold‐to‐Hot Transition and Immune‐Cure in Glioblastoma

Advanced Science, EarlyView.
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang, Pan‐Pan Gao, Yu‐Wen Du, Li‐Qin Wu, En‐Zhi Yin, Qi An, Ze‐Hua Ding, Jin‐Wen Shi, Ya Shu, Ruoqiao Chen, Feng Liu, Mingfeng Li, Xiao Qian Chen   +12 more
wiley   +1 more source

ROLE OF OMEGA-3 FATTY ACIDS ON POSTPARTUM DEPRESSION [PDF]

Introduction: Women in child-bearing age are at risk of postpartum depression. Several drugs have been introduced for treatment, but because of their side effects and also breast feeding women's desire for dietary complements rather than chemical drugs ...
قوجازاده, مرتضی, نوروزی پناهی, لیلا, رنجبر کوچکسرایی, فاطمه, ایوان بقاء, ریحانه   +3 more
core   +1 more source

Experiences of HIV-positive postpartum women and health workers involved with community-based antiretroviral therapy adherence clubs in Cape Town, South Africa

BMC Public Health, 2018
Background The rollout of universal, lifelong treatment for all HIV-positive pregnant and breastfeeding women (“Option B+”) has rapidly increased the number of women initiating antiretroviral treatment (ART) and requiring ART care postpartum.
Zara Trafford, Yolanda Gomba, Christopher J. Colvin, Victoria O. Iyun, Tamsin K. Phillips, Kirsty Brittain, Landon Myer, Elaine J. Abrams, Allison Zerbe   +8 more
doaj   +1 more source

NSD2 Coordinates the Neurogenic‐to‐Gliogenic Transition via H3K36me2‐Dependent Activation of the EGFR‐ERK Pathway

Advanced Science, EarlyView.
NSD2 coordinates the neurogenic‐to‐gliogenic transition in the developing neocortex through H3K36me2‐dependent activation of EGFR–ERK signaling. Loss of NSD2 disrupts astroglial and oligodendroglial development, whereas ERK activation rescues gliogenic defects in vitro and in vivo.
Hanxue Chen, Mengyuan Li, Lin Hou, Bin Yin, Boqin Qiang, Ran Gao, Pengcheng Shu, Xiaozhong Peng   +7 more
wiley   +1 more source

Postpartum eclampsia of late onset [PDF]

, 2005
Pre-eclampsia and eclampsia occur in 6% to 8% of all pregnancies.1 The British eclampsia study confirmed 383 cases of eclampsia during 1992 and warned of the severe consequences of the condition.2 In 1997 Leitch and colleagues showed that over a 60 year ...
Valentine, A., Hardiman, P., Maclean, A.B., Lipman, M., Munjuluri, N.   +4 more
core  

Effectiveness of Cold Compress and Lavender Aromatherapy on Reduction in Postpartum Perineal Pain Intensity [PDF]

, 2020
Introduction: Every postpartum mother got a perineal wound and experience pain. This pain results in unpleasant effect such as fear of movement which can lead to problems such as sub uterine involution, unhealthy release of lochea, and postpartum ...
Qomariah, Siti Nur, Fatmawati, Lilis, Runis, Aidatur, Syaiful, Yuanita   +3 more
core   +1 more source

Traditional Belief and Practice on Postpartum Recovery among Mothers in East Coast of Peninsular Malaysia

MATEC Web of Conferences, 2018
Postpartum care is highly important to prevent maternal and infant morbidity. In Malaysia, there are several traditional postpartum care practices by mothers. Different states adopted different ways to perform those practices.
Abdul Ghani Radiah, Salehudin Saezah
doaj   +1 more source

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source